Fig. 5
From: GSDMD gene knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice
GSDMD-KO prevents transcriptional changes induced by hyperoxia in the hippocampus. A Principal component analysis (PCA) plot showing separation of WT and GSDMD-KO mice by PC1 and WT-RA and WT-O2 animals by PC3, but no separation between KO-O2 and KO-RA. B Heatmap of differentially expressed genes in WT-O2 vs. WT-RA and KO-O2 vs. KO RA with hierarchical clustering of treatment groups. n = 4 animals/group in WT groups. n = 3 animals/group in KO groups