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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Sexually dimorphic extracellular vesicle responses after chronic spinal cord injury are associated with neuroinflammation and neurodegeneration in the aged brain

Fig. 3

Long-term SCI alters transcription of genes related to neuropathology in the hippocampus. A PLSDA of normalized gene counts revealed distinct clustering by injury and biological sex. B Number of DEGs (p-value < 0.05) in each set of pairwise comparison. C Heatmap of pathway signature scores for DEGs in the hippocampus. D Bar graph of pathway signature scores for top 5 pathways downregulated by SCI in males and the top upregulated pathway in SCI/M group. n = 5–6 mice/group

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Journal of Neuroinflammation

ISSN: 1742-2094