Fig. 8

Plasma EV subtypes are increased robustly in males at 19 months post-injury. A, B Western blot was performed on total plasma EVs for tetraspanin EV markers CD63 (A) and CD81 (B) with quantification of densitometry showing robust increase in SCI/M compared to Sham/M. C–E Nanoparticle Tracking Analysis (NTA) was performed on the same samples with particle concentration (C) and mean/mode particle size (D, E) shown. n = 9 for sham groups and 12 for SCI groups. *p < 0.05, **p < 0.01 vs. Sham group. Multiple Mann–Whitney U tests for pairwise comparison