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Table 1 miRNA cargo of tissue derived EVs are affected by sex and injury interaction

From: Sexually dimorphic extracellular vesicle responses after chronic spinal cord injury are associated with neuroinflammation and neurodegeneration in the aged brain

Probes

â–² ORâ–¼ Linear MFI fold change

SCI vs. Sham

Female vs. Male

Spinal cord

Male

Female

Sham

SCI

hsa-miR-301a-3p

2.21

0.56

2.06

0.52

hsa-miR-98-5p

0.81

1.85

0.99

2.26

Cortex

hsa-mir-382-5p

1.40

0.96

1.11

0.76

hsa-mir-151a-3p

2.43

0.92

1.45

0.55

Hippocampus

hsa-miR-451a

0.95

0.12

4.28

0.53

hsa-miR-181b-5p

0.85

1.21

0.86

1.22

  1. Linear fold change of the mean fluorescent intensity (MFI) data between relevant groups are shown, with either Sham or Male as the reference groups. n = 6/group for spinal cord EVs; n = 7/group for cortex and hippocampus EVs
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Journal of Neuroinflammation

ISSN: 1742-2094