Skip to main content

Table 2 Tissue and circulating EV miR cargo is modified by biological sex

From: Sexually dimorphic extracellular vesicle responses after chronic spinal cord injury are associated with neuroinflammation and neurodegeneration in the aged brain

Probes

â–² ORâ–¼

Linear MFI fold change

adj. p-value

Hippocampus

 hsa-miR-21-5p

â–²

3.52

*

 hsa-miR-7-5p

â–²

2.34

*

 hsa-let-7f-5p

â–²

2.06

*

 hsa-miR-338-3p

â–²

1.70

*

 hsa-miR-146a-5p

â–²

1.58

*

 hsa-miR-124-3p

â–¼

0.69

*

 hsa-miR-34a-5p

â–¼

0.63

**

Spinal cord

 hsa-let-7f-5p

â–²

2.06

**

 hsa-miR-195-5p

â–²

1.80

*

 hsa-miR-370-3p

â–²

1.64

*

 hsa-miR-98-5p

â–²

1.56

*

 hsa-let-7g-5p

â–²

1.46

*

 hsa-miR-17-5p

â–²

1.39

*

 hsa-let-7b-5p

â–²

1.34

*

Plasma

 hsa-miR-214-3p

â–²

1.76

*

 hsa-miR-103a-3p

â–¼

0.82

*

  1. Linear fold change of the mean fluorescent intensity (MFI) data between groups are shown as well as adjusted (adj.) p-value of significance. For all data, male is used as the reference group. n = 6/group for plasma and spinal cord EVs, n = 7/group for cortex and hippocampus. *p < 0.05, **p < 0.01 vs male group. Two-way ANOVA following Tukey’s multiple comparisons test