Fig. 4

Atorvastatin does not alter astrocyte end-feet. Representative images of AQP4 staining in the frontal cortex of mice on control (A), control + ATO (B), HHcy (C), and HHcy + ATO diet (D). Percent area (E), average vessel area (F), average vessel length (G) and vessels/mm² (H) in the frontal cortex are shown for AQP4. Percent area (I), average vessel area (J), average vessel length (K) and vessels/mm² (L) in the hippocampus are shown for AQP4. Representative images of DP71 staining in the frontal cortex of mice on control (M), control + ATO (N), HHcy (O), and HHcy + ATO diet (P). Scale bar in A and M = 100 µm; scale bar in A is for images A–D and scale bar in M is for images M–P. Percent area (Q), average vessel area (R), average vessel length (S) and vessels/mm² (T) in the frontal cortex are shown for DP71. Percent area (U), average vessel area (V), average vessel length (W) and vessels/mm² (X) in the hippocampus are shown for DP71