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Table 1 Patient’s characteristics

From: Distinct features of B cell receptors in neuromyelitis optica spectrum disorder among CNS inflammatory demyelinating diseases

 

NMOSD (n = 13)

MOGAD (n = 12)

DSN (n = 8)

HC (n = 34)

p

Age, median (IQR)

58.0 (49.0–63.0)

59.0 (44.5–61.3)

46.0 (36.8–55.3)

30.0 (27.0–32.8)

 < 0.001

Age at onset, median (IQR)

47.0 (43.0–51.5)

46.5 (19.5–57.0)

40.0 (23.5–46.5)

–

0.365

Female, n (%)

10 (76.9)

8 (66.7)

4 (50.0)

19 (55.9)

0.506

Number of attacks, median (IQR)

2.0 (1.0–3.0)

2.0 (1.5–3.0)

2.5 (1.3–3.0)

–

0.677

 Optic neuritis

0.0 (0.0–1.0)

1.0 (0.0–3.0)

0.0 (0.0–0.8)

–

0.056

 Brain

0.0 (0.0–1.0)

0.0 (0.0–0.8)

0.0 (0.0–0.0)

–

0.649

 Myelitis

1.0 (1.0–2.5)

0.0 (0.0–1.0)

2.0 (0.3–3.0)

–

0.005

Disease duration, median (IQR)

7.7 (4.7–12.1)

5.9 (4.1–15.7)

8.7 (5.9–20.0)

–

0.696

Immune-modulating treatmenta, n (%)

13 (100.0)

8 (66.7)

2 (25.0)

–

0.001

EDSS, median (IQR)

2.0 (2.0–3.8)

2.0 (1.1–4.3)

3.0 (1.5–4.6)

–

0.196

  1. p-values < 0.05 were indicated in bold
  2. DSN, double-seronegative; EDSS, Expanded Disability Status Scale; MOGAD, myelin oligodendrocyte glycoprotein associated disorder; NMOSD, neuromyelitis optica spectrum disorder
  3. aImmune-modulating treatment including azathioprine and oral prednisolone