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Table 1 Features of viruses infecting CNS and possibilities of preventing the disease

From: Metabolic response to CNS infection with flaviviruses

Features

Enterviruses

MuV

Flaviviruses

LCMV

Herpes-viruses

Genetic material of the virus

DNA

RNA

RNA

RNA

DNA

Presence of envelope

−

 + 

 + 

 + 

 + 

Route of infection

Food-borne, droplet direct contact

Droplet

Vector-borne

By rodents

Droplet direct contact

Symptoms

Most common from the skin and mucous membranes, less often from the muscles and nervous system

Typical: fever and swelling in the parotid gland area, rarely the nervous system

Nervous system infection

Nervous system infection

Can cause infection of the nervous system

Existing vaccines

Polio virus, HAV

+ 

JEV, TBEV, DENV

ZIKV—phase I clinical trials

−

VZV