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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Inhibition of neutrophil extracellular trap formation ameliorates neuroinflammation and neuronal apoptosis via STING-dependent IRE1α/ASK1/JNK signaling pathway in mice with traumatic brain injury

Fig. 2

The effects of Cl-amidine treatment on short-term neurological functions, cerebral lesion volume, brain edema, and CBF after TBI. A–D mNSS test (A), Rotarod test (B), Cylinder test (C), and Corner test (D) at 1 day post-TBI. *p < 0.05, **p < 0.01, ***p < 0.001, n = 10 per group E–H mNSS test (E), Rotarod test (F), Cylinder test (G), and Corner test (H) at 3 days post-TBI. *p < 0.05, **p < 0.01, ***p < 0.001, n = 10 per group. I Representative images of serial coronal sections labeled by Nissl and quantitative analysis of tissue loss at 3 days after TBI. Scale bar = 1 mm, *p < 0.05, ***p < 0.001, n = 8 per group. J Representative images of MRI scanning at 1 day and 3 days after TBI and quantitative analysis of brain edema volume at 1 day and 3 days after TBI. *p < 0.05 ***p < 0.001, n = 8 per group. K Representative images of CBF by LSCI in different groups at different time points after TBI and quantitative analysis of continuous CBF changes before and after CCI. *p < 0.05, **p < 0.01, ***p < 0.001, n = 8 per group

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Journal of Neuroinflammation

ISSN: 1742-2094