Fig. 4
From: Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity
NFIA knockdown reverses 4-AP-induced hippocampal astrocyte state transition. A Scheme of animal preparation for immunohistochemical assay and protein analysis. B Immunohistochemical staining of GFAP in the hippocampal tissues from the mice with si.NC/si.NFIA delivery and ip. 4-AP/saline. Ci Representative immunoblot bands of S100A10, GFAP, NFIA and C3 in hippocampal tissues from the mice with si. NC/si. NFIA delivery and ip. 4-AP/saline, and the band density analysis of Cii S100A10, Ciii GFAP, Civ NFIA, and Cv C3 (n = 3 for each group, *P < 0.05, **P < 0.01, ***P < 0.001, One-way ANOVA)