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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Astrocyte interferon-gamma signaling dampens inflammation during chronic central nervous system autoimmunity via PD-L1

Fig. 1

IFNγ signaling induces the PD-1/PD-L1 axis in astrocytes. Modulated Ingenuity Pathway Analysis (A) pathways and (B) signaling networks following 24-h stimulation of primary human astrocytes with 10 ng/ml IFNγ and RNA sequencing. C A two-way ANOVA with Tukey’s multiple comparison test was performed on read counts of differentially expressed genes relevant to the PD-1/PD-L1 axis. Data represent the mean ± SEM from 3 independent samples. ****P < 0.0001

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Journal of Neuroinflammation

ISSN: 1742-2094