Fig. 4
Nr4a1−/− mice show increased laser-induced CNV area. A–C Representative choroidal wholemounts of a single CNV lesion from WT, Nr4a1−/−, and Nr4a1se2/se2 mice. D–F Laser-induced CNV area per mouse for all animals, female, and male mice. N = 22–53 mice per group. Kruskal–Wallis test followed by Dunn’s multiple comparisons test *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. G, H Representative choroidal sprouts from WT and Nr4a1−/− eyes. I Average angiogenesis area was equivalent between groups. N = 14–15. Student’s unpaired t test