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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Recombinant Slit2 suppresses neuroinflammation and Cdc42-mediated brain infiltration of peripheral immune cells via Robo1–srGAP1 pathway in a rat model of germinal matrix hemorrhage

Fig. 5

Effects of recombinant Slit2 on neuronal death in brain at 5 days after GMH. TUNEL staining showed the degree of DNA breakage (A) was aggravated after GMH, which were reduced by rSlit2. “*” symbol indicates the lesion location on the representative microphotograph of brain slice. Scale bar = 100 μm. Western blotting image and quantitative analysis showed that brain cleaved caspase-3 (B) expressions increased after GMH, which were reduced by rSlit2. N = 6/group. Mean ± SEM. ANOVA, Tukey. *P < 0.05 vs. Sham, #P < 0.05 vs. GMH + Vehicle

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Journal of Neuroinflammation

ISSN: 1742-2094