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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Recombinant Slit2 suppresses neuroinflammation and Cdc42-mediated brain infiltration of peripheral immune cells via Robo1–srGAP1 pathway in a rat model of germinal matrix hemorrhage

Fig. 8

Effects of srGAP siRNA on recombinant Slit2-mediated downregulation of peripheral immune cells infiltration into brain. Western blotting analysis showed that the downregulation of brain MPO (A) and CD68 (B) expressions by recombinant Slit2 were reversed by srGAP1 siRNA in GMH rats. N = 6/group. Mean ± SEM. ANOVA, Tukey. #P < 0.05 vs. GMH + Vehicle, @P < 0.05 vs. GMH + rSlit2. &P < 0.05 vs. GMH + rSlit2 + srGAP1 siRNA

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Journal of Neuroinflammation

ISSN: 1742-2094