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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Ly6C-high monocytes alleviate brain injury in experimental subarachnoid hemorrhage in mice

Fig. 4

A Percentage of Ly6C-high monocytes, Ly6C-low monocytes, and macrophages in mouse brains determined by flow cytometry on day 1 post-surgery (sham group, n = 5; SAH group, n = 6). B CCR2 (green)-positive cells (white arrow) in the ipsilateral basal cortex of the mice were assessed by immunofluorescence staining on day 1 post-surgery (n = 3/group). C Distribution of monocytes in the peripheral blood of healthy controls, SAH patients with Hunt-Hess scores < 4 and SAH patients with Hunt-Hess scores ≥ 4 (healthy controls, n = 347; Hunt-Hess < 4, n = 310; Hunt-Hess ≥ 4, n = 55). D ROC curve showing the discriminating value of monocytes in the peripheral blood between SAH patients with Hunt-Hess scores < 4 and SAH patients with Hunt-Hess scores ≥ 4 (Hunt-Hess < 4, n = 310; Hunt-Hess ≥ 4, n = 55). E The correlation between peripheral blood monocytes and the Hunt-Hess score (n = 365). ns, P ≥ 0.05; *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001

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