Skip to main content
Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Ly6C-high monocytes alleviate brain injury in experimental subarachnoid hemorrhage in mice

Fig. 6

A, B ssGSEA scores of the MONOCYTE_CHEMOTAXIS and POSITIVE_REGULATION_OF_MONOCYTE_CHEMOTAXIS pathways in GSE79416 and our data. C, D FPKM values of Ccl1, Ccl2, Ccl3, Ccl4, Ccl5, Ccl6, Ccl7, Ccl8, Ccl9, Cx3cl1, Ccr1, Ccr2, Ccr8, and Cx3cr1 in GSE79416 and our data. E The mRNA expression levels of Ccl2, Ccl3, Ccl4, Ccl5, Ccl6, Ccl7, Ccl8, and Ccl9 in the mouse brains on day 1 post-surgery were assessed by qPCR (n = 6/group). F The mRNA expression levels of Ccl2, Ccl3, Ccl4, and Ccl7 in CD11b-positive and -negative cells isolated from sham and SAH mouse brains on day 1 post-surgery were assessed by MACS (sham group, n = 3; SAH group, n = 4). G, H The percentage of Ly6C-high monocytes and the ratio of Ly6C-high monocytes to neutrophils in the brains of mice in the SAH + vehicle and SAH + mino groups on day 1 post-surgery were assessed by flow cytometry (n = 5/group). I, J The percentage of Ly6C-high monocytes and the ratio of Ly6C-high monocytes to neutrophils in the brains of mice in the SAH + vehicle and SAH + DT groups on day 1 post-surgery were assessed by flow cytometry (n = 6/group). K, L The percentage of Ly6C-high monocytes and the ratio of Ly6C-high monocytes to neutrophils in the brains of mice in the SAH + IgG and SAH + αCCL2 groups on day 1 post-surgery were assessed by flow cytometry (n = 6/group). ns, P ≥ 0.05, *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001

Back to article page