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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Microglial activation, tau and amyloid deposition in TREM2 p.R47H carriers and mild cognitive impairment patients: a multi-modal/multi-tracer PET/MRI imaging study with influenza vaccine immune challenge

Fig. 1

Baseline comparison of regional microglial activation. TSPO DVR values across Braak stages, comparing HC, MCI and TREM2 p.R47H carriers, showing lower DVR in Braak II and Braak III regions in TREM2 p.R47H carriers. Box plots show median values, interquartile range and range. Statistical comparisons between the TREM2 p.R47H group and each of the control groups separately, with age and TSPO status as covariates. * P < 0.05. DVR  distribution volume ratio, HC  health control, MCI  mild cognitive impairment, TSPO  translocator protein

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Journal of Neuroinflammation

ISSN: 1742-2094