Table 1 Demographics and clinical characteristics of the participants in this study
Characteristics | NLRP3&miRNA study cohort (n = 450) | p value | IL-1β study cohort (n = 228) | p value | miRNA sequencing cohort (n = 10) | p value | Correlation analysis cohort | p value | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
HC (n = 226) | PD (n = 224) | HC (n = 112) | PD (n = 116) | HC (n = 5) | PD (n = 5) | PD (n = 98) | |||||
Age a | 67.39 ± 9.71 | 67.35 ± 9.84 | NSb | 67.47 ± 9.08 | 67.5 ± 9.58 | NSb | 72 ± 4.6 | 72.2 ± 4.32 | NSb | 68.33 ± 9.64 | NSb |
Gender (M: F) | 135: 91 | 133: 91 | NSc | 66: 46 | 69: 47 | NSc | 3: 2 | 3: 2 | NSc | 58: 40 | NSc |
Disease duration (years)a | NA | 5.76 ± 4.2 | NA | NA | 5.8 ± 4.3 | NA | NA | 7.8 ± 7.56 | NA | 5.69 ± 4.06 | NA |
Hoehn and Yahr scorea | NA | 2.3 ± 1.03 | NA | NA | 2.26 ± 0.74 | NA | NA | 2.5 ± 1.1 | NA | 2.28 ± 0.8 | NA |