Table 2 Between-group comparisons of baseline demographics, APOE-ε4 carrier status in the longitudinal subsample
ATN groups (n) | Statistical tests p (p.adj) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Stable CN A−/T−/N− (77) | Stable A+/T−/N− (18) | Stable A+/T+ or N+ (89) | Stable A−/T+ or N+ (29) | F/χ2/η2 (p) | A−/T−/N− vs. A+/T−/N− | A−/T−/N− vs. A+/T+ or N+ | A−/T−/N− vs. A−/T+ or N+ | A+/T+/N+ vs. A−/T+ or N+ | |
Age mean (SD) | 60.04 (8.83) | 66.17 (8.34) | 68.70 (6.78) | 66.52 (9.10) | F = 16.56, η2 = 0.15 (< 0.001) | a< 0.01 (< 0.05) | a< .001 (< 0.001) | a< .001 (< 0.001) | an.s (n.s.) |
Female n (%) | 42 (54.54) | 14 (77.78) | 43 (48.31) | 14 (48.28) | χ2 = 5.55, (0.135) | b | b | b | b |
APOE-ε4+ n (%) [missing n] | 28 (36.36) [n = 0] | 13 (72.22) [n = 0] | 66 (74.16) [n = 1] | 10 (34.48) [n = 0] | χ2 = 32.14, (< 0.001) | b | b | b | b |
Recruited as controls n (%) | 25 (32.47) | 1 (5.56) | 10 (11.24) | 4 (13.79) | b | b | b | b | |
SCD n (%) | 52 (67.53) | 7 (38.89) | 23 (25.84) | 13 (44.83) | b | b | b | b | |
MCI n (%) | 0 (0) | 10 (55.55) | 56 (62.92) | 12 (41.38) | b | b | b | b | |
*CN n (%)/*MCI n (%) | 77 (100)/0 (0) | 7 (38.89)/11 (61.11) | 28 (31.46)/61 (68.54) | 17 (58.62)/12 (41.38) | **χ2 = 8.90, (< 0.01) | b | b | b | b |