Fig. 5
From: Oxygen therapy attenuates neuroinflammation after spinal cord injury
Impact of SCI and O2 treatment on tidal volume, rate, and minute ventilation. Examples of respiratory waveforms recorded using whole body plethysmography are shown in panel A. Inspiration is shown as an upward deflection. Panels B, C show mean results during normoxic (21% O2) breathing on day 5 and day 10 post-SCI, respectively. After normoxic baseline recordings, a brief (5-min) challenge was induced by flowing a reduced O2 (10%) and increased CO2 (7%) gas mixture through the plethysmography chamber. This was done to test the capacity to increase breathing; mean results are shown in panels D, E. A one-way analysis of variance was used to determine group differences, if a data-set failed ANOVA assumptions a Kruskal–Wallis (KW) test was run. The omnibus effect of group p-value is noted in the figure; *indicates p < 0.05 Dunnet’s post-hoc compared to Intact