Fig. 5
From: Autophagy dysfunction contributes to NLRP1 inflammasome-linked depressive-like behaviors in mice
Rapamycin ameliorates CSDS-induced depressive-like behavior in mice. A Scheme of rapamycin treatment, social defeat stress and behavior test. B–F Representative traces and statistical results show that rapamycin increased the total moving distance (B–D) and the social interaction (E, F) in depressive-like mice. G–I Statistical results show that rapamycin increased sucrose preference (G) and decreased immobility time during TST (H) and FST (I) in depressive-like mice. Data are expressed as means ± SEM, n = 6. Data were expressed as means ± SEM. *p < 0.05, **p < 0.01 vs. control group or CSDS group