Fig. 1

Metabolic analysis between the CAT group and wAMD group. A Heatmap analysis between the two groups. B Metabonomic pathway analysis. C Different metabolites in the TCA cycle according to the KEGG database. D Display of meaningful metabolites in the TCA cycle. Red represents elevated expression, and blue represents decreased expression. E–L Specific concentrations of pyruvate, citrate, cis-aconitate, isocitrate, α-ketoglutarate, succinate, l-malate and fumarate (n = 5). *P < 0.05, **P < 0.01, ***P < 0.001