Fig. 7

The effects of dopamine on T and B cells. A The proliferative effects of dopamine on lymphocytes by CCK-8. B AChR-specific antibody in the supernatant were measured using ELISA. Statistical analysis was performed using one-way ANOVA in Panel A and B, multiple comparisons were performed using Dunnett’s test with the DA concentration of 0 μmol/L. C The incubation of dopamine significantly increased the percentage of Th1 and Th17 cells, while the proportion of Treg cells remained unchanged. D Incubated dopamine led to a significant increase in the percentage of CD138, MHC II⁺ and CD69⁺ B cells, while the proportions of CD80 and CD86 B cells remained unchanged. Statistical analysis was performed using t tests in Panel C and D, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, ns = no significant difference