Fig. 2

C-Mito entered ECs in the SFO of HF mice. A Fluorescent tracing of pre-stained C-Mito showed C-Mito were significantly enriched in the SFO. Scale bar = 100 μm. B Analysis showed the number of C-Mito accumulated in the SFO of HF mice was significantly higher than that in the SFO of control mice, while the number of C-Mito^HF entering the SFO was similar to that of C-Mito^Ctrl. C Immunofluorescent staining showed C-Mito were mainly entered the ECs of the SFO in HF mice. Scale bar = 50 μm. D Analysis showed that the number of C-Mito^HF entering the ECs of the SFO was similar to that of C-Mito^Ctrl. n = 8, P < 0.05, ANOVA LSD test