Fig. 8From: Increased regulatory activity of intestinal innate lymphoid cells type 3 (ILC3) prevents experimental autoimmune encephalomyelitis severityEffects of Cpd1 on PLNC. DA rats were immunized with SCH and treated orally with Cpd1 (15 mg/kg, q.d.) or vehicle (water) 0–5 d.p.i. Subsequently, PLNC were isolated and counted (A). Percentage of cell populations was determined by flow cytometry (B–I). PLNC were exposed to MBP for 48 h and IFN-γ and IL-17 levels in cell culture supernatants were determined by ELISA (J, K). Data are presented as mean ± SD (n = 5–10, from 2 to 4 independent experiments). *p < 0.05, ns—not significantBack to article page