Fig. 7

Regulation pattern of GR target genes in Müller cells of the diabetic mouse. A Accessibility at peaks associated with the GR (Nr3c1) motif is plotted comparing results from Müller cells isolated from 6-month-old control and db/db animals (n = 2 for each genotype). B Plots of transcript expression of GR target genes as determined by the RNA-seq experiment on purified retinal cell types from 6-month-old animals. Bars represent mean ± SEM from 3 biological replicates per genotype. Unpaired t-test: *p < 0.05; **p < 0.01