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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Microbiota-derived acetate attenuates neuroinflammation in rostral ventrolateral medulla of spontaneously hypertensive rats

Fig. 8

Acetate significantly increased intestinal flora metabolites in SHRs. A, PCA analysis showing spatial division for the fecal metabolome. B, the volcano plot graph of altered metabolites in control WKY rats and SHRs. C, the heatmap displays the top 25 metabolites with significant differential abundance between control WKY rats and SHRs. D, bubble plot showing the differential metabolic pathways analysis of fecal metabolites in control WKY rats and SHRs. E, the volcano plot illustrates the profile of metabolites altered in SHRs treated with acetate compared to control SHRs. F, the heatmap depicts the 25 most significantly differentially abundant metabolites when comparing acetate treatment SHRs to control SHRs. G, the bubble plot presents an analysis of the differential metabolic pathways associated with fecal metabolites in SHRs treated with acetate versus control SHRs

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Journal of Neuroinflammation

ISSN: 1742-2094