Fig. 1

Controlled cortical impact produces a significant decline in visual function. A Schematic of injury location. Mice receive a craniotomy and a single right-sided impact on the dura B Mice experience deficits in visual acuity as measured by the optomotor response after injury, with most mice experiencing a complete loss in contralateral vision, and a significant decrease in ipsilateral visual acuity. C Representative images of cortical tissue loss following TBI. B, paired t-test. ***p < 0.001