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Journal of Neuroinflammation

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  1. Content type: Research

    Chemokine CXC receptor 4 (CXCR4) in spinal glial cells has been implicated in neuropathic pain. However, the regulatory cascades of CXCR4 in neuropathic pain remain elusive. Here, we investigated the functiona...

    Authors: Zhiqiang Pan, Qun Shan, Pan Gu, Xiao Min Wang, Lydia Wai Tai, Menglan Sun, Xin Luo, Liting Sun and Chi Wai Cheung

    Citation: Journal of Neuroinflammation 2018 15:29

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  2. Content type: Research

    Microglia function is essential to maintain the brain homeostasis. Evidence shows that aged microglia are primed and show exaggerated response to acute inflammatory challenge. Systemic inflammation signals to ...

    Authors: Joana Costa d’Avila, Luciana Domett Siqueira, Aurélien Mazeraud, Estefania Pereira Azevedo, Debora Foguel, Hugo Caire Castro-Faria-Neto, Tarek Sharshar, Fabrice Chrétien and Fernando Augusto Bozza

    Citation: Journal of Neuroinflammation 2018 15:28

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  3. Content type: Research

    Traumatic brain injury (TBI) is a critical public health and socio-economic problem worldwide. A growing body of evidence supports the involvement of inflammatory events in TBI. It has been reported that resid...

    Authors: Atsuko Katsumoto, Aline S. Miranda, Oleg Butovsky, Antônio L. Teixeira, Richard M. Ransohoff and Bruce T. Lamb

    Citation: Journal of Neuroinflammation 2018 15:26

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  4. Content type: Research

    We attempted to determine whether the inflammatory pathway HMGB1-TLR4 and the downstream pro-inflammatory cytokines is upregulated in focal cortical dysplasia (FCD) type II and whether there is a correlation b...

    Authors: Zhongbin Zhang, Qingzhu Liu, Ming Liu, Hui Wang, Ying Dong, Taoyun Ji, Xiaoyan Liu, Yuwu Jiang, Lixin Cai and Ye Wu

    Citation: Journal of Neuroinflammation 2018 15:27

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  5. Content type: Research

    Secoisolariciresinol diglucoside (SDG), the main lignan in flaxseed, is known for its beneficial effects in inflammation, oxidative stress, heart disease, tumor progression, atherosclerosis, and diabetes. SDG ...

    Authors: Slava Rom, Viviana Zuluaga-Ramirez, Nancy L. Reichenbach, Michelle A. Erickson, Malika Winfield, Sachin Gajghate, Melpo Christofidou-Solomidou, Kelly L. Jordan-Sciutto and Yuri Persidsky

    Citation: Journal of Neuroinflammation 2018 15:25

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  6. Content type: Research

    Baló’s concentric sclerosis (BCS) is a rare inflammatory demyelinating disorder of the central nervous system characterised by concentric layers of demyelination. It is unclear whether BCS is a variant of mult...

    Authors: S. Jarius, C. Würthwein, J. R. Behrens, J. Wanner, J. Haas, F. Paul and B. Wildemann

    Citation: Journal of Neuroinflammation 2018 15:22

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  7. Content type: Research

    Varicella zoster virus (VZV) reactivation spans the spectrum from uncomplicated segmental herpes zoster to life-threatening disseminated CNS infection. Moreover, in the absence of a small animal model for this...

    Authors: Maike Kuhn, Kurt-Wolfram Sühs, Manas K. Akmatov, Frank Klawonn, Junxi Wang, Thomas Skripuletz, Volkhard Kaever, Martin Stangel and Frank Pessler

    Citation: Journal of Neuroinflammation 2018 15:20

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  8. Content type: Research

    Depression is a heterogeneous disorder, with the exact neuronal mechanisms causing the disease yet to be discovered. Recent work suggests it is accompanied by neuro-inflammation, characterized, in particular, ...

    Authors: Ya-Lin Wang, Qiu-Qin Han, Wen-Qing Gong, Dong-Hui Pan, Li-Zheng Wang, Wei Hu, Min Yang, Bing Li, Jin Yu and Qiong Liu

    Citation: Journal of Neuroinflammation 2018 15:21

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  9. Content type: Research

    Neuroprotection with cannabinoids in Parkinson’s disease (PD) has been afforded predominantly with antioxidant or anti-inflammatory cannabinoids. In the present study, we investigated the anti-inflammatory and...

    Authors: Concepción García, María Gómez-Cañas, Sonia Burgaz, Belén Palomares, Yolanda Gómez-Gálvez, Cristina Palomo-Garo, Sara Campo, Joel Ferrer-Hernández, Carolina Pavicic, Carmen Navarrete, M. Luz Bellido, Moisés García-Arencibia, M. Ruth Pazos, Eduardo Muñoz and Javier Fernández-Ruiz

    Citation: Journal of Neuroinflammation 2018 15:19

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  10. Content type: Research

    It is debated whether multiple sclerosis (MS) might result from an immunopathological response toward an active Epstein-Barr virus (EBV) infection brought into the central nervous system (CNS) by immigrating B...

    Authors: Caterina Veroni, Barbara Serafini, Barbara Rosicarelli, Corrado Fagnani and Francesca Aloisi

    Citation: Journal of Neuroinflammation 2018 15:18

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  11. Content type: Research

    Redox signaling, which can be assessed by circulating aminothiols, reflects oxidative stress (OS) status and has been linked to clinical cardiovascular disease and its risk factors. These, in turn, are related...

    Authors: Ihab Hajjar, Salim S. Hayek, Felicia C. Goldstein, Greg Martin, Dean P. Jones and Arshed Quyyumi

    Citation: Journal of Neuroinflammation 2018 15:17

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  12. Content type: Research

    Current options to treat clinical relapse in inflammatory central nervous system (CNS) conditions such as cerebral ischemia-reperfusion injury are limited, and agents that are more effective are required. Disr...

    Authors: Dong-Dong Zhang, Chen Jin, Ya-Tao Zhang, Xiang-Dong Gan, Min-Ji Zou, Yuan-Yuan Wang, Wen-Liang Fu, Tao Xu, Wei-Wei Xing, Wen-Ron Xia and Dong-Gang Xu

    Citation: Journal of Neuroinflammation 2018 15:16

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  13. Content type: Research

    Immune and inflammatory responses occurring in the spinal cord play a pivotal role in the progression of radicular pain caused by intervertebral disk herniation. Interleukin-33 (IL-33) orchestrates inflammator...

    Authors: Si-Jian Huang, Jian-Qin Yan, Hui Luo, Lu-Yao Zhou and Jian-Gang Luo

    Citation: Journal of Neuroinflammation 2018 15:12

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  14. Content type: Research

    Parkinson’s disease (PD) is the most prevalent neurodegenerative disorder that is characterised by selective loss of midbrain dopaminergic (DA) neurons. Chronic inflammation of the central nervous system is me...

    Authors: Longping Yao, Yongyi Ye, Hengxu Mao, Fengfei Lu, Xiaozheng He, Guohui Lu and Shizhong Zhang

    Citation: Journal of Neuroinflammation 2018 15:13

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  15. Content type: Research

    Age-related macular degeneration (AMD) is a devastating eye disease causing irreversible vision loss in the elderly. Retinal pigment epithelium (RPE), the primary cell type that is afflicted in AMD, undergoes ...

    Authors: Jiangyuan Gao, Jing Z. Cui, Eleanor To, Sijia Cao and Joanne A. Matsubara

    Citation: Journal of Neuroinflammation 2018 15:15

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  16. Content type: Correction

    After publication of the article [1], it has been brought to our attention that an author’s name has been formatted incorrectly.

    Authors: Elizabeth Nance, Siva P. Kambhampati, Elizabeth S. Smith, Zhi Zhang, Fan Zhang, Sarabdeep Singh, Michael V. Johnston, Rangaramanujam M. Kannan, Mary E. Blue and Sujatha Kannan

    Citation: Journal of Neuroinflammation 2018 15:14

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    The original article was published in Journal of Neuroinflammation 2017 14:252

  17. Content type: Research

    The consumption of large amounts of dietary fats activates an inflammatory response in the hypothalamus, damaging key neurons involved in the regulation of caloric intake and energy expenditure. It is currentl...

    Authors: Albina F. Ramalho, Bruna Bombassaro, Nathalia R. Dragano, Carina Solon, Joseane Morari, Milena Fioravante, Roberta Barbizan, Licio A. Velloso and Eliana P. Araujo

    Citation: Journal of Neuroinflammation 2018 15:10

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  18. Content type: Research

    Chronic high-fat diet (HFD) consumption caused not only obese-insulin resistance, but also cognitive decline and microglial hyperactivity. Modified gut microbiota by prebiotics and probiotics improved obese-in...

    Authors: Titikorn Chunchai, Wannipa Thunapong, Sakawdaurn Yasom, Keerati Wanchai, Sathima Eaimworawuthikul, Gabrielle Metzler, Anusorn Lungkaphin, Anchalee Pongchaidecha, Sasithorn Sirilun, Chaiyavat Chaiyasut, Wasana Pratchayasakul, Parameth Thiennimitr, Nipon Chattipakorn and Siriporn C. Chattipakorn

    Citation: Journal of Neuroinflammation 2018 15:11

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  19. Content type: Research

    Targeting the endocannabinoid system has emerged as an effective strategy for the treatment of inflammatory and neurological diseases. Unlike the inhibition of the principal 2-arachidonyl glycerol (2-AG) hydro...

    Authors: Jie Wen, Melissa Jones, Mikiei Tanaka, Prabhuanand Selvaraj, Aviva J. Symes, Brian Cox and Yumin Zhang

    Citation: Journal of Neuroinflammation 2018 15:9

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  20. Content type: Research

    Neuroinflammation is implicated in the development and progression of many neurodegenerative diseases. Conditions that lead to a peripheral immune response are often associated with inflammation in the central...

    Authors: Jing Jing Li, Bin Wang, Mahesh Chandra Kodali, Chao Chen, Eunhee Kim, Benjamin John Patters, Lubin Lan, Santosh Kumar, Xinjun Wang, Junming Yue and Francesca-Fang Liao

    Citation: Journal of Neuroinflammation 2018 15:8

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  21. Content type: Research

    Previous studies have demonstrated that oral administration of curcumin exhibited an anti-arthritic effect despite its poor bioavailability. The present study aimed to explore whether the gut-brain axis is inv...

    Authors: Yannong Dou, Jinque Luo, Xin Wu, Zhifeng Wei, Bei Tong, Juntao Yu, Ting Wang, Xinyu Zhang, Yan Yang, Xusheng Yuan, Peng Zhao, Yufeng Xia, Huijuan Hu and Yue Dai

    Citation: Journal of Neuroinflammation 2018 15:6

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  22. Content type: Research

    Exposure of the developing brain to immune mediators, including antibodies, is postulated to increase risk for neurodevelopmental disorders and neurodegenerative disease. It has been suggested that immunoglobu...

    Authors: Marianna Stamou, Ana Cristina Grodzki, Marc van Oostrum, Bernd Wollscheid and Pamela J. Lein

    Citation: Journal of Neuroinflammation 2018 15:7

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  23. Content type: Research

    Cognitive impairment is one of common complications of acute respiratory distress syndrome (ARDS). Increasing evidence suggests that interleukin-1 beta (IL-1β) plays a role in inducing neuronal apoptosis in co...

    Authors: Hong-Guang Ding, Yi-Yu Deng, Ren-qiang Yang, Qiao-Sheng Wang, Wen-Qiang Jiang, Yong-Li Han, Lin-Qiang Huang, Miao-Yun Wen, Wen-Hong Zhong, Xu-Sheng Li, Fan Yang and Hong-Ke Zeng

    Citation: Journal of Neuroinflammation 2018 15:4

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