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Table 1 Counts of Iba1-positive cell bodies in the cortex and hippocampus from the two treatment cohorts

From: Cognitive and cerebrovascular improvements following kinin B1 receptor blockade in Alzheimer’s disease mice

SSR 5 weeks

WT (n = 5)

WT-SSR (n = 5)

APP (n = 5)

APP-SSR (n = 4)

Cortex

542.5 ± 19.3

546.1 ± 46.5

536.3 ± 29.5

497.2 ± 8.8

Hippocampus

532.4 ± 36.8

553.9 ± 57.3

524.2 ± 37.1

518.2 ± 16.4

Dentate gyrus

418.1 ± 50.6

464.5 ± 62.9

439.6 ± 29.1

433.0 ± 60.8

SSR 10 weeks

WT (n = 5)

WT-SSR (n = 5)

APP (n = 5)

APP-SSR (n = 5)

Cortex

529.9 ± 27.1

557.8 ± 18.1

549.5 ± 11.9

576.4 ± 50.9

Hippocampus

608.2 ± 15.4

624.8 ± 33.2

669.8 ± 35.9

679.3 ± 62.2

Dentate gyrus

419.0 ± 22.7

423.9 ± 22.6

468.9 ± 15.2

466.0 ± 44.4

  1. Data are means ± SEM from the number (n) of mice indicated in parentheses. Iba1 ionized calcium-binding adaptor molecule 1, SSR SSR240612, WT wild-type, APP amyloid precursor protein.