Figure 2
From: Human CNS cultures exposed to HIV-1 gp120 reproduce dendritic injuries of HIV-1-associated dementia
Gp120 exposure results in astrocytic hypertrophy and a reduction in dendritic complexity. Representative immunofluorescent images from 4-week monolayer control cultures (a) and cultures exposed to gp120 for 72 hours (b) stained for C3βT (green) and GFAP (red). Neuronal processes in the gp120 exposed condition appear reduced, sinuous, varicosed and vacuolated in comparison to controls. All bars = 20 μm.