Ellis RJ, Deutsch R, Heaton RK, Marcotte TD, McCutchan JA, Nelson JA, Abramson I, Thal LJ, Atkinson JH, Wallace MR, Grant I: Neurocognitive impairment is an independent risk factor for death in HIV infection. San Diego HIV Neurobehavioral Research Center Group. Arch Neurol. 1997, 54: 416-424.
Article
CAS
PubMed
Google Scholar
Clifford DB: Human immunodeficiency virus-associated dementia. Arch Neurol. 2000, 57: 321-324. 10.1001/archneur.57.3.321.
Article
CAS
PubMed
Google Scholar
Kaul M, Garden GA, Lipton SA: Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature. 2001, 410: 988-994. 10.1038/35073667.
Article
CAS
PubMed
Google Scholar
Sacktor N, McDermott MP, Marder K, Schifitto G, Selnes OA, McArthur JC, Stern Y, Albert S, Palumbo D, Kieburtz K, De Marcaida JA, Cohen B, Epstein L: HIV-associated cognitive impairment before and after the advent of combination therapy. J Neurovirol. 2002, 8: 136-142.
Article
PubMed
Google Scholar
McArthur JC, Hoover DR, Bacellar H, Miller EN, Cohen BA, Becker JT, Graham NM, McArthur JH, Selnes OA, Jacobson LP: Dementia in AIDS patients: incidence and risk factors. Multicenter AIDS Cohort Study. Neurology. 1993, 43: 2245-2252.
Article
CAS
PubMed
Google Scholar
Dore GJ, Correll PK, Li Y, Kaldor JM, Cooper DA, Brew BJ: Changes to AIDS dementia complex in the era of highly active antiretroviral therapy. AIDS. 1999, 13: 1249-1253. 10.1097/00002030-199907090-00015.
Article
CAS
PubMed
Google Scholar
Ferrando S, van Gorp W, McElhiney M, Goggin K, Sewell M, Rabkin J: Highly active antiretroviral treatment in HIV infection: benefits for neuropsychological function. AIDS. 1998, 12: F65-F70. 10.1097/00002030-199808000-00002.
Article
CAS
PubMed
Google Scholar
Sacktor NC, Lyles RH, Skolasky RL, Anderson DE, McArthur JC, McFarlane G, Selnes OA, Becker JT, Cohen B, Wesch J, Miller EN: Combination antiretroviral therapy improves psychomotor speed performance in HIV-seropositive homosexual men. Multicenter AIDS Cohort Study (MACS). Neurology. 1999, 52: 1640-1647.
Article
CAS
PubMed
Google Scholar
Major EO, Rausch D, Marra C, Clifford D: HIV-associated dementia. Science. 2000, 288: 440-442. 10.1126/science.288.5465.439d.
Article
CAS
PubMed
Google Scholar
Lipton SA: Treating AIDS dementia. Science. 1997, 276: 1629-1630. 10.1126/science.276.5319.1629b.
Article
CAS
PubMed
Google Scholar
Walsh K, Thompson W, Megyesi J, Wiley CA, Hammond R: HIV-/AIDS Neuropathology in a canadian teaching centre. Can J Neurol Sci. 2003, in press:
Google Scholar
Masliah E, Ge N, Achim CL, Hansen LA, Wiley CA: Selective neuronal vulnerability in HIV encephalitis. J Neuropathol Exp Neurol. 1992, 51: 585-593.
Article
CAS
PubMed
Google Scholar
Everall IP, Glass JD, McArthur J, Spargo E, Lantos P: Neuronal density in the superior frontal and temporal gyri does not correlate with the degree of human immunodeficiency virus-associated dementia. Acta Neuropathol (Berl). 1994, 88: 538-544. 10.1007/s004010050196.
Article
CAS
Google Scholar
Masliah E, Achim CL, Ge N, DeTeresa R, Terry RD, Wiley CA: Spectrum of human immunodeficiency virus-associated neocortical damage. Ann Neurol. 1992, 32: 321-329.
Article
CAS
PubMed
Google Scholar
Everall IP, Heaton RK, Marcotte TD, Ellis RJ, McCutchan JA, Atkinson JH, Grant I, Mallory M, Masliah E: Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder. HNRC Group. HIV Neurobehavioral Research Center. Brain Pathol. 1999, 9: 209-217.
Article
CAS
PubMed
Google Scholar
Dreyer EB, Kaiser PK, Offermann JT, Lipton SA: HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists. Science. 1990, 248: 364-367.
Article
CAS
PubMed
Google Scholar
Kaiser PK, Offermann JT, Lipton SA: Neuronal injury due to HIV-1 envelope protein is blocked by anti-gp120 antibodies but not by anti-CD4 antibodies. Neurology. 1990, 40: 1757-1761.
Article
CAS
PubMed
Google Scholar
Lipton SA, Sucher NJ, Kaiser PK, Dreyer EB: Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity. Neuron. 1991, 7: 111-118. 10.1016/0896-6273(91)90079-F.
Article
CAS
PubMed
Google Scholar
Catani MV, Corasaniti MT, Navarra M, Nistico G, Finazzi-Agro A, Melino G: gp120 induces cell death in human neuroblastoma cells through the CXCR4 and CCR5 chemokine receptors. J Neurochem. 2000, 74: 2373-2379. 10.1046/j.1471-4159.2000.0742373.x.
Article
CAS
PubMed
Google Scholar
Kaul M, Lipton SA: Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis. Proc Natl Acad Sci U S A. 1999, 96: 8212-8216. 10.1073/pnas.96.14.8212.
Article
PubMed Central
CAS
PubMed
Google Scholar
Pandey V, Bolsover SR: Immediate and neurotoxic effects of HIV protein gp120 act through CXCR4 receptor. Biochem Biophys Res Commun. 2000, 274: 212-215. 10.1006/bbrc.2000.3113.
Article
CAS
PubMed
Google Scholar
Catani MV, Corasaniti MT, Ranalli M, Amantea D, Litovchick A, Lapidot A, Melino G: The Tat antagonist neomycin B hexa-arginine conjugate inhibits gp-120-induced death of human neuroblastoma cells. J Neurochem. 2003, 84: 1237-1245. 10.1046/j.1471-4159.2003.01620.x.
Article
CAS
PubMed
Google Scholar
Nath A, Haughey NJ, Jones M, Anderson C, Bell JE, Geiger JD: Synergistic neurotoxicity by human immunodeficiency virus proteins Tat and gp120: protection by memantine. Ann Neurol. 2000, 47: 186-194. 10.1002/1531-8249(200002)47:2<186::AID-ANA8>3.3.CO;2-V.
Article
CAS
PubMed
Google Scholar
Corder EH, Robertson K, Lannfelt L, Bogdanovic N, Eggertsen G, Wilkins J, Hall C: HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy. Nat Med. 1998, 4: 1182-1184. 10.1038/2677.
Article
CAS
PubMed
Google Scholar
Zemlyak I, Brooke SM, Sapolsky RM: Protection against gp120-induced neurotoxicity by an array of estrogenic steroids. Brain Res. 2002, 958: 272-276. 10.1016/S0006-8993(02)03558-8.
Article
CAS
PubMed
Google Scholar
Brooke SM, Sapolsky RM: Effects of glucocorticoids in the gp120-induced inhibition of glutamate uptake in hippocampal cultures. Brain Res. 2003, 972: 137-141. 10.1016/S0006-8993(03)02517-4.
Article
CAS
PubMed
Google Scholar
Scorziello A, Florio T, Bajetto A, Schettini G: Intracellular signalling mediating HIV-1 gp120 neurotoxicity. Cell Signal. 1998, 10: 75-84. 10.1016/S0898-6568(97)00093-4.
Article
CAS
PubMed
Google Scholar
Bruce-Keller AJ: Microglial-neuronal interactions in synaptic damage and recovery. J Neurosci Res. 1999, 58: 191-201. 10.1002/(SICI)1097-4547(19991001)58:1<191::AID-JNR17>3.3.CO;2-5.
Article
CAS
PubMed
Google Scholar
Giulian D, Vaca K, Noonan CA: Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1. Science. 1990, 250: 1593-1596.
Article
CAS
PubMed
Google Scholar
Giulian D, Wendt E, Vaca K, Noonan CA: The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes. Proc Natl Acad Sci U S A. 1993, 90: 2769-2773.
Article
PubMed Central
CAS
PubMed
Google Scholar
Chao CC, Hu S, Molitor TW, Shaskan EG, Peterson PK: Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J Immunol. 1992, 149: 2736-2741.
CAS
PubMed
Google Scholar
Boje KM, Arora PK: Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res. 1992, 587: 250-256. 10.1016/0006-8993(92)91004-X.
Article
CAS
PubMed
Google Scholar
Brooke SM, Sapolsky RM: Glucocorticoid exacerbation of gp120 neurotoxicity: role of microglia. Exp Neurol. 2002, 177: 151-158. 10.1006/exnr.2002.7956.
Article
CAS
PubMed
Google Scholar
Dugas N, Lacroix C, Kilchherr E, Delfraissy JF, Tardieu M: Role of CD23 in astrocytes inflammatory reaction during HIV-1 related encephalitis. 2001, 15: 96-107.
Google Scholar
Pozzoli G, Tringali G, Dello Russo C., Vairano M, Preziosi P, Navarra P: HIV-1 Gp120 protein modulates corticotropin releasing factor synthesis and release via the stimulation of its mRNA from the rat hypothalamus in vitro: involvement of inducible nitric oxide synthase. J Neuroimmunol. 2001, 118: 268-276. 10.1016/S0165-5728(01)00351-4.
Article
CAS
PubMed
Google Scholar
Howard SA, Nakayama AY, Brooke SM, Sapolsky RM: Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures. Exp Neurol. 1999, 158: 164-170. 10.1006/exnr.1999.7080.
Article
CAS
PubMed
Google Scholar
Brandimarti R, Khan MZ, Fatatis A, Meucci O: Regulation of cell cycle proteins by chemokine receptors: A novel pathway in human immunodeficiency virus neuropathogenesis?. J Neurovirol. 2004, 10 (Suppl 1): 108-112. 10.1080/13550280490268287.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hammond RR, Iskander S, Achim CL, Hearn S, Nassif J, Wiley CA: A reliable primary human CNS culture protocol for morphological studies of dendritic and synaptic elements. J Neurosci Methods. 2002, 118: 189-198. 10.1016/S0165-0270(02)00126-7.
Article
PubMed
Google Scholar
Martin FC, Wiley CA: A serum-free, pyruvate-free medium that supports neonatal neural/glial cultures. J Neurosci Res. 1995, 41: 246-258.
Article
CAS
PubMed
Google Scholar
White MG, Hammond RR, Sanders VJ, Bonaroti EA, Mehta AP, Wang G, Wiley CA, Achim CL: Neuron-enriched second trimester human cultures: growth factor response and in vivo graft survival. Cell Transplant. 1999, 8: 59-73.
CAS
PubMed
Google Scholar
Masliah E, Heaton RK, Marcotte TD, Ellis RJ, Wiley CA, Mallory M, Achim CL, McCutchan JA, Nelson JA, Atkinson JH, Grant I: Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. HNRC Group. The HIV Neurobehavioral Research Center. Ann Neurol. 1997, 42: 963-972.
Article
CAS
PubMed
Google Scholar
McArthur JC, Sacktor N, Selnes O: Human immunodeficiency virus-associated dementia. Semin Neurol. 1999, 19: 129-150.
Article
CAS
PubMed
Google Scholar
Adle-Biassette H, Chretien F, Wingertsmann L, Hery C, Ereau T, Scaravilli F, Tardieu M, Gray F: Neuronal apoptosis does not correlate with dementia in HIV infection but is related to microglial activation and axonal damage. Neuropathol Appl Neurobiol. 1999, 25: 123-133. 10.1046/j.1365-2990.1999.00167.x.
Article
CAS
PubMed
Google Scholar
Dawson VL, Dawson TM, Uhl GR, Snyder SH: Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures. Proc Natl Acad Sci U S A. 1993, 90: 3256-3259.
Article
PubMed Central
CAS
PubMed
Google Scholar
Cai L, Cherian MG, Iskander S, Leblanc M, Hammond RR: Metallothionein induction in human CNS in vitro: neuroprotection from ionizing radiation. Int J Radiat Biol. 2000, 76: 1009-1017. 10.1080/09553000050051025.
Article
CAS
PubMed
Google Scholar