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Figure 9 | Journal of Neuroinflammation

Figure 9

From: In vivo temporal and spatial profile of leukocyte adhesion and migration after experimental traumatic brain injury in mice

Figure 9

Representative images of superficial vessels in following administration of anti-CD18 antibodies or control IgG. (A,B) Rolling and particularly adhering leukocytes and aggregates in cerebral venules 14 h after controlled cortical impact. The animals received either control IgG (A) or anti-CD18 antibodies (B). (C,D) Cerebral microcirculation at lower magnification (note the difference in scale bases compared with A and B). The animals received either control IgG (C) or anti-CD18 antibodies (D). After administration of anti-CD18 antibodies the adherence of both leukocytes and aggregates to the venular endothelium was significantly reduced (B,D).

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