Figure 9

MCH-II expression in the retinal layers after 15 days of unilateral laser-induced OHT. MHC-II immunostaining. Retinal whole-mounts. In naïve eyes (A, D, G, J), Iba-1+ cells had a weak constitutive MHC-II expression (arrow) except for the dendritic-like cells in the IPL which had an intense constitutive MHC-II expression (arrowhead in D). In contralateral (B, E, H, K) and OHT eyes (C, F, I, L) MHC-II was upregulated in all retinal layers. (NFL-GCL: nerve fiber layer-ganglion cell layer; IPL: inner plexiform layer; OHT: ocular hypertension; OPL: outer plexiform layer; OS: photoreceptor outer segment).