Skip to main content

Table 2 IL-1 family cytokine and receptor levels in CSF and serum of sALS patients

From: Evaluating the levels of interleukin-1 family cytokines in sporadic amyotrophic lateral sclerosis

Cytokine/Receptor CSF Serum
ALS Controls ALS Controls
IL-1β <7.8 <7.8 <7.8 (n = 1; 47.2) <7.8 (n = 1; 26.6)
IL-1Ra <78.1 <78.1 (n = 1; 101.7) <78.1 (n = 1; 547.4) <78.1
sIL-1R2 <312.5 <312.5 (n = 1; 325.7) 5673.4 ± 2771.5 5575.0 ± 1359.5
IL-33 <30.0 (n = 3; 72.9 ± 32.3) <30.0 (n = 3; 54.8 ± 27.1) 625.4 ± 1570.5 536.3 ± 1166.3
sIL-1R4 <62.5 (n = 4; 85.1 ± 13.2) <62.5(n = 2; 85.5 ± 3.9) 72.4 ± 16.4 79.9 ± 28.3
IL-37 <46.8 <46.8 <46.8 <46.8 (n = 1; 74.7)
IL-36 NT NT 888.3 ± 729.3 1531.7 ± 1843.2
  1. Values are given as mean pg/ml ± SD rather than in nM since the MW of the mature forms of the cytokines and of the natural soluble receptors are not yet precisely defined.
  2. CSF, Cerebrospinal fluid; n, Number of samples above the detection limit; NT, Not tested; sALS, sporadic amyotrophic lateral sclerosis.