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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Small interfering RNA-mediated suppression of Ccl2 in Müller cells attenuates microglial recruitment and photoreceptor death following retinal degeneration

Figure 2

Relative expression of Ccl2 in the retina measure by quantitative PCR following small interfering (si)RNA injection and light damage. In animals injected with Ccl2 siRNA, expression of Ccl2 decreased significantly to 29.3% relative to the Invivofectamine-only control group after 24 hours BCL (P < 0.05; ANOVA/Tukey’s test), whereas expression of Ccl2 in animals injected with scrambled siRNA did not change appreciably compared with the Invivofectamine-only group (95.4%, P < 0.05; ANOVA/Tukey’s test). Inivofectamine-only (n = 8), scrambled siRNA (n = 8), Ccl2 siRNA (n = 6). Error bars represent SEM. *Significant change at P <0.05 using ANOVA with Tukey’s post hoc test.

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Journal of Neuroinflammation

ISSN: 1742-2094