Figure 1
![Figure 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2F1742-2094-9-85/MediaObjects/12974_2012_571_Fig1_HTML.jpg)
CRH augments VEGF release from IgE/anti-IgE-stimulated human mast cells, and increases FcεRI gene expression. (A) VEGF secretion from LAD2 cells was measured after pretreatment with CRH 10 μmol/l for 24 hours, followed by 2 hours of incubation with IgE 1 microgram/μl in response to anti-IgE 10 μg/ml. (B) FcεRI mRNA expression was assessed after stimulation of hCBMCs with CRH (0.1, 1, 10 μmol/l) for 6 hours. For all experiments, n = 5; *p < 0.05, **p < 0.01, ***p < 0.001 compared with control.