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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies

Figure 4

Neutralization of endogenous quinolinic acid (QUIN) with an anti-QUIN monoclonal antibody (mAb). (a) The schematic diagram represents the effect of QUIN mAb on IFN-γ-treated BV2 supernatant in N19 and N20.1 oligodendroglial cell lines. (b) represents the levels of lactate dehydrogenase (LDH) released by oligodendroglial cell lines N19 and N20.1, respectively after 72 hours incubation with IFN-γ-treated BV2 and varying concentrations of QUIN mAb. The study was performed in triplicate and the error bars indicate SE. ***P < 0.001.

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Journal of Neuroinflammation

ISSN: 1742-2094