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Retraction Note: Bone mesenchymal stem cell-derivedexosomal microRNA-29b-3p preventshypoxic-ischemic injury in rat brain byactivating the PTEN-mediated Aktsignaling pathway

The Original Article was published on 03 February 2020

Retraction to: J Neuroinflammation 17, 46 (2020)

https://doi.org/10.1186/s12974-020-1725-8

The authors have retracted this article [1] because they have been unable to replicate the results of their study. After publication they expanded the sample size and repeated the measurements, and found that miR-29b-3p was not always down-regulated in the rat MCAO model and OGD cell model. In addition, when the processing time was doubled, miR-29b-3p showed an upward trend. The conclusions presented are therefore not reliable. All authors agree with this retraction.

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  1. 1.

    Hou K, Li G, Zhao J, Xu B, Yang Z, Yu J, Kan X. Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway. J Neuroinflammation. 2020;17:46 https://doi.org/10.1186/s12974-020-1725-8.

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Correspondence to Jinlu Yu or Kan Xu.

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Hou, K., Li, G., Zhao, J. et al. Retraction Note: Bone mesenchymal stem cell-derivedexosomal microRNA-29b-3p preventshypoxic-ischemic injury in rat brain byactivating the PTEN-mediated Aktsignaling pathway. J Neuroinflammation 17, 352 (2020). https://doi.org/10.1186/s12974-020-02034-6

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