Skip to main content

Correction to: Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury

The Original Article was published on 05 January 2019

Correction to: Journal of Neuroinflammation (2019) 16:2 https://doi.org/10.1186/s12974-018-1383-2

The original version [1] of the article unfortunately contained mistakes in Figs. 5 and 6. The mistake occurred due to a copying and labeling error with image selection; all analyses remain the same.

It has been corrected in this correction (Figs. 5 and 6).

Fig. 5
figure 5

Astrocytes labelled with GFAP antibody in the frontal cortex and hippocampus. A A significant reduction in GFAP-positive cells was seen in TBI + MSCs (***p < 0.001) and TBI + MSCs + IL-10 (***p < 0.001) groups in the frontal cortex in comparison to TBI + vehicle group. B In the CA1 region of the hippocampus, a significant reduction of GFAP positive cells were found in the TBI + MSCs + IL-10 (***p < 0.001) and sham + vehicle group (*p < 0.05) in comparison to TBI + vehicle group. C In the CA3 region of the hippocampus, TBI + vehicle group had a significant increase in GFAP-positive cells when compared to all other groups (*p < 0.05, **p < 0.01; scale bar = 50 µm). Error bars represent ± SEM

Fig. 6
figure 6

Macrophages/microglia labelled with Iba1 antibody in the frontal cortex and hippocampus. A In the frontal cortex an injury effect was seen with an increased number of Iba1 positive cells in all TBI groups (*p < 0.05, ***p < 0.001). B No significant differences were seen among the groups in the CA1 region of the hippocampus. C No significant differences were seen among the groups in the CA3 region of the hippocampus (scale bar = 50 µm). Error bars represent ± SEM

Reference

  1. Peruzzaro ST, Andrews MM, Al-Gharaibeh A, Pupiec O, Resk M, Story D, Maiti P, Rossignol J, Dunbar GL. Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury. J Neuroinflamm. 2019;16:2.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to J. Rossignol or G. L. Dunbar.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Peruzzaro, S.T., Andrews, M.M.M., Al-Gharaibeh, A. et al. Correction to: Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury. J Neuroinflammation 19, 15 (2022). https://doi.org/10.1186/s12974-021-02362-1

Download citation

  • Published:

  • DOI: https://doi.org/10.1186/s12974-021-02362-1