Fig. 6
Expression of candidate neurologic genes is significantly dysregulated following subcutaneous inoculation with ZIKV-DAK-MA in hSTAT2 knockin mice. A qRT-PCR analysis of ZIKV RNA in the brains of 5-week-old hSTAT2 knockin mice at indicated day post-infection (dpi) following subcutaneous inoculation with ZIKV-DAK-MA (103 PFU). Values are reported in plaque forming unit-equivalents (PFUe) per hemisphere of brain tissue. n = 5–7 mice/group. B-O Expression profiles of 14 candidate genes assessed by qRT-PCR analysis on indicated days following intracranial ZIKV-DAK-MA infection. n = 5–7 mice/group. * p < 0.05, ** p < 0.01, *** p < 0.001. Bars represent group means