Fig. 4

HsTx2 alleviates IL-1β-induced astrocyte inflammation by upregulating circ_0001293. a, b RT–qPCR was used to determine the expression of circ_0001293. c Cell viability was detected using the CCK-8 assay. d ELISAs were conducted to determine the levels of TNF-α, IFN-γ, IL-6, IL-10 and TGF-β2. ^***P < 0.001 compared with NC; ^###P < 0.001 compared with IL-1β; ^&&P < 0.01 and ^&&&P < 0.001 compared with IL-1β + HsTx2. All values are presented as the means ± SD (n = 3)