Fig. 7

HsTx2 alleviates IL-1β-induced astrocyte inflammation via the circ_0001293/miR-8114/TGF-β2 axis. a RT–qPCR was used to determine the expression of circ_0001293, miR-8114 and TGF-β2. b Cell viability was detected using the CCK-8 assay. c ELISAs were conducted to determine the levels of TNF-α, IFN-γ, IL-6, IL-10 and TGF-β2. d Levels of MAPK- and NF-κB-related proteins were determined using Western blotting. ^***P < 0.001 compared with NC; ^###P < 0.001 compared with IL-1β; ^&P < 0.05, ^&&P < 0.01 and ^&&&P < 0.001 compared with IL-1β + HsTx2. All values are presented as the means ± SD (n = 3)