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Correction: Fluoxetine regulates eEF2 activity (phosphorylation) via HDAC1 inhibitory mechanism in an LPS-induced mouse model of depression

Journal of Neuroinflammation volume 19, Article number: 317 (2022) Cite this article

The Original Article was published on 01 February 2021

Correction : Journal of Neuroinflammation (2021) 18:38 https://doi.org/10.1186/s12974-021-02091-5

Following publication of the original article [1], the authors identified an error in Fig. 5. The correct version of figure is given below.

Fig. 5
figure 5

Fluoxetine attenuated LPS effect on mTOR/eEF2/BDNF/SNAP25/PSD95 and HDACs. a Representative immune blot images and average protein levels of b p-mTOR, c p-eEF2, d BDNF, e PSD95, f SNAP25, g 5HT2A, and h 5HT-2C. i–k Average level of HDAC1, HDAC2, and HDAC3 levels, respectively. l, m Golgi staining showing spine density and column graph showing spin numbers. Image Lab Software was used for blot quantitative analysis and was analyzed via GraphPad prism. Data were expressed as ± SEM, one-way ANOVA followed by post hoc analysis. p ≤ 0.05 were considered significant. *p < 0.05, **p < 0.01), ***p < 0.001, ****p < 0.0001

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The original article has been corrected.

Reference

  • Li W, Ali T, Zheng C, Liu Z, He K, Shah FA, Ren Q, Rahman SU, Li N, Yu Z-J, Li S. Fluoxetine regulates eEF2 activity (phosphorylation) via HDAC1 inhibitory mechanism in an LPS-induced mouse model of depression. Journal of Neuroinflammation. 2021;18:38. https://doi.org/10.1186/s12974-021-02091-5.

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Authors and Affiliations

  1. State Key Laboratory of Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China

    Weifen Li, Tahir Ali, Chengyou Zheng, Zizhen Liu, Kaiwu He, Fawad Ali Shah, Shafiq Ur Rahman & Shupeng Li

  2. Riphah Institute of Pharmaceutical Sciences, Riphah International University Islamabad, Islamabad, Pakistan

    Fawad Ali Shah

  3. Department of Neurology, Affiliated ZhongDa Hospital, School of Medicine, Southeast University, Nanjing, China

    Qingguo Ren

  4. Department of Pharmacy, Shaheed Benazir Bhutto University, Sheringal, Dir, 18000, Pakistan

    Shafiq Ur Rahman

  5. Tomas Lindahl Nobel Laureate Laboratory, Precision Medicine Research Centre, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, 518107, China

    Ningning Li

  6. Department of Infectious Diseases and Shenzhen Key Laboratory for Endogenous Infections, The 6Th Affiliated Hospital of Shenzhen University Health Science Center, No. 89, Taoyuan Road, Nanshan District, Shenzhen, 518052, China

    Zhi-Jian Yu

  7. Campbell Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada

    Shupeng Li

  8. Department of Psychiatry, University of Toronto, Toronto, ON, Canada

    Shupeng Li

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  1. Weifen Li
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  2. Tahir Ali
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  9. Ningning Li
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  10. Zhi-Jian Yu
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Correspondence to Zhi-Jian Yu or Shupeng Li.

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Li, W., Ali, T., Zheng, C. et al. Correction: Fluoxetine regulates eEF2 activity (phosphorylation) via HDAC1 inhibitory mechanism in an LPS-induced mouse model of depression. J Neuroinflammation 19, 317 (2022). https://doi.org/10.1186/s12974-022-02649-x

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  • DOI: https://doi.org/10.1186/s12974-022-02649-x

Journal of Neuroinflammation

ISSN: 1742-2094