Fig. 4

Changes in serum neurofilament light chain (sNfl) with oral GlcNAc. A–D Averaged sNfL before (V1–4), during (V5–8), and after (V9–11) oral GlcNAc individually (A, B) or combined (C, D) in subjects with median baseline sNfL ≥ 11.07 pg/ml. n = 9 and n = 8 in the 6 g (A, C) and 12 g (B, D) cohorts, respectively. sNfL measured by SIMOA. P value by linear mixed modeling (one-tailed) in subjects who completed the study