Na KS, Jung HY, Kim YK. The role of pro-inflammatory cytokines in the neuroinflammation and neurogenesis of schizophrenia. Prog Neuro-Psychopharmacol Biol Psychiatry. 2014;48:277–86.
Meyer U, Feldon J, Yee BK. A review of the fetal brain cytokine imbalance hypothesis of schizophrenia. Schizophr Bull. 2009;35:959–72.
Hughes HK, Mills Ko E, Rose D, Ashwood P. Immune dysfunction and autoimmunity as pathological mechanisms in autism spectrum disorders. Front Cell Neurosci. 2018;12:405.
Dammann O, Leviton A. Maternal intrauterine infection, cytokines, and brain damage in the preterm newborn. Pediatr Res. 1997;42:1–8.
Knuesel I, Chicha L, Britschgi M, Schobel SA, Bodmer M, Hellings JA, Toovey S, Prinssen EP. Maternal immune activation and abnormal brain development across CNS disorders. Nat Rev Neurol. 2014;10:643–60.
Garay PA, McAllister AK. Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders. Front Synaptic Neurosci. 2010;2:136.
Deverman BE, Patterson PH. Cytokines and CNS development. Neuron. 2009;64:61–78.
Goines PE, Croen LA, Braunschweig D, Yoshida CK, Grether J, Hansen R, Kharrazi M, Ashwood P, Van de Water J. Increased midgestational IFN-gamma, IL-4 and IL-5 in women bearing a child with autism: a case-control study. Mol Autism. 2011;2:13.
Jones KL, Croen LA, Yoshida CK, Heuer L, Hansen R, Zerbo O, DeLorenze GN, Kharrazi M, Yolken R, Ashwood P, Van de Water J. Autism with intellectual disability is associated with increased levels of maternal cytokines and chemokines during gestation. Mol Psychiatry. 2017;22:273–9.
Brown AS, Hooton J, Schaefer CA, Zhang H, Petkova E, Babulas V, Perrin M, Gorman JM, Susser ES. Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring. Am J Psychiatry. 2004;161:889–95.
Buka SL, Tsuang MT, Torrey EF, Klebanoff MA, Wagner RL, Yolken RH. Maternal cytokine levels during pregnancy and adult psychosis. Brain Behav Immun. 2001;15:411–20.
Bodnar TS, Raineki C, Wertelecki W, Yevtushok L, Plotka L, Zymak-Zakutnya N, Honerkamp-Smith G, Wells A, Rolland M, Woodward TS, et al. Altered maternal immune networks are associated with adverse child neurodevelopment: impact of alcohol consumption during pregnancy. Brain Behav Immun. 2018;73:205–15.
Muggli E, Matthews H, Penington A, Claes P, O'Leary C, Forster D, Donath S, Anderson PJ, Lewis S, Nagle C, et al. Association between prenatal alcohol exposure and craniofacial shape of children at 12 months of age. JAMA Pediatr. 2017;171:771–80.
Keiver K, Bertram CP, Orr AP, Clarren S. Salivary cortisol levels are elevated in the afternoon and at bedtime in children with prenatal alcohol exposure. Alcohol. 2015;49:79–87.
Caputo C, Wood E, Jabbour L. Impact of fetal alcohol exposure on body systems: a systematic review. Birth Defects Res C Embryo Today. 2016;108:174–80.
Tsang TW, Lucas BR, Carmichael Olson H, Pinto RZ, Elliott EJ. Prenatal alcohol exposure, FASD, and child behavior: a meta-analysis. Pediatrics. 2016;137:e20152542.
Wozniak JR, Mueller BA, Mattson SN, Coles CD, Kable JA, Jones KL, Boys CJ, Lim KO, Riley EP, Sowell ER, Cifasd: Functional connectivity abnormalities and associated cognitive deficits in fetal alcohol Spectrum disorders (FASD). Brain Imaging Behav 2017;11:1432–1445.
May PA, Chambers CD, Kalberg WO, Zellner J, Feldman H, Buckley D, Kopald D, Hasken JM, Xu R, Honerkamp-Smith G, et al. Prevalence of fetal alcohol spectrum disorders in 4 US communities. JAMA. 2018;319:474–82.
Baio J, Wiggins L, Christensen DL, Maenner MJ, Daniels J, Warren Z, Kurzius-Spencer M, Zahorodny W, Robinson Rosenberg C, White T, et al. Prevalence of autism spectrum disorder among children aged 8 years - autism and developmental disabilities monitoring network, 11 sites, United States, 2014. MMWR Surveill Summ. 2018;67:1–23.
Gauthier TW. Prenatal alcohol exposure and the developing immune system. Alcohol Res. 2015;37:279–85.
Johnson S, Knight R, Marmer DJ, Steele RW. Immune deficiency in fetal alcohol syndrome. Pediatr Res. 1981;15:908–11.
Gauthier TW, Manar MH, Brown LA. Is maternal alcohol use a risk factor for early-onset sepsis in premature newborns? Alcohol. 2004;33:139–45.
Kvigne VL, Leonardson GR, Borzelleca J, Neff-Smith M, Welty TK. Hospitalizations of children who have fetal alcohol syndrome or incomplete fetal alcohol syndrome. S D Med. 2009;62:97, 99, 101–3.
Libster R, Ferolla FM, Hijano DR, Acosta PL, Erviti A, Polack FP, Network IR. Alcohol during pregnancy worsens acute respiratory infections in children. Acta Paediatr. 2015;104:e494–9.
Linneberg A, Petersen J, Gronbaek M, Benn CS. Alcohol during pregnancy and atopic dermatitis in the offspring. Clin Exp Allergy. 2004;34:1678–83.
Wada K, Konishi K, Tamura T, Shiraki M, Iwasa S, Nagata C. Alcohol intake during pregnancy and offspring’s atopic eczema risk. Alcohol Clin Exp Res. 2016;40:1037–43.
Gottesfeld Z, Abel EL. Maternal and paternal alcohol use: effects on the immune system of the offspring. Life Sci. 1991;48:1–8.
Reid N, Moritz KM, Akison LK. Adverse health outcomes associated with fetal alcohol exposure: a systematic review focused on immune-related outcomes. Pediatr Allergy Immunol. 2019;30:698–707.
Bodnar T, Weinberg J. Prenatal alcohol exposure: impact on neuroendocrine-neuroimmune networks. In: Cui C, Grandison L, Noronha A, editors. Neural-Immune Interactions in Brain Function and Alcohol Related Disorders. New York: Springer; 2013. p. 312–62.
Ahluwalia B, Wesley B, Adeyiga O, Smith DM, Da-Silva A, Rajguru S. Alcohol modulates cytokine secretion and synthesis in human fetus: an in vivo and in vitro study. Alcohol. 2000;21:207–13.
Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah I, Van de Water J. Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome. Brain Behav Immun. 2011;25:40–5.
Manzardo AM, Henkhaus R, Dhillon S, Butler MG. Plasma cytokine levels in children with autistic disorder and unrelated siblings. Int J Dev Neurosci. 2012;30:121–7.
Okada K, Hashimoto K, Iwata Y, Nakamura K, Tsujii M, Tsuchiya KJ, Sekine Y, Suda S, Suzuki K, Sugihara G, et al. Decreased serum levels of transforming growth factor-beta1 in patients with autism. Prog Neuro-Psychopharmacol Biol Psychiatry. 2007;31:187–90.
Rose D, Ashwood P. Potential cytokine biomarkers in autism spectrum disorders. Biomark Med. 2014;8:1171–81.
Trovao N, Prata J, VonDoellinger O, Santos S, Barbosa M, Coelho R. Peripheral biomarkers for first-episode psychosis-opportunities from the neuroinflammatory hypothesis of schizophrenia. Psychiatry Investig. 2019;16:177–84.
Krakowiak P, Goines PE, Tancredi DJ, Ashwood P, Hansen RL, Hertz-Picciotto I, Van de Water J. Neonatal cytokine profiles associated with autism spectrum disorder. Biol Psychiatry. 2017;81:442–51.
Dinarello CA. Historical insights into cytokines. Eur J Immunol. 2007;37(Suppl 1):S34–45.
Becher B, Spath S, Goverman J. Cytokine networks in neuroinflammation. Nat Rev Immunol. 2017;17:49–59.
Morel PA, Lee REC, Faeder JR. Demystifying the cytokine network: mathematical models point the way. Cytokine. 2017;98:115–23.
Coles CD, Kable JA, Keen CL, Jones KL, Wertelecki W, Granovska IV, Pashtepa AO, Chambers CD, Cifasd: Dose and timing of prenatal alcohol exposure and maternal nutritional supplements: developmental effects on 6-month-old infants. Matern Child Health J 2015;19:2605–2614.
Chambers CD, Yevtushok L, Zymak-Zakutnya N, Korzhynskyy Y, Ostapchuk L, Akhmedzhanova D, Chan PH, Xu R, Wertelecki W. Prevalence and predictors of maternal alcohol consumption in 2 regions of Ukraine. Alcohol Clin Exp Res. 2014;38:1012–9.
Mattson SN, Foroud T, Sowell ER, Jones KL, Coles CD, Fagerlund A, Autti-Ramo I, May PA, Adnams CM, Konovalova V, et al. Collaborative initiative on fetal alcohol spectrum disorders: methodology of clinical projects. Alcohol. 2010;44:635–41.
Barr HM, Streissguth AP. Identifying maternal self-reported alcohol use associated with fetal alcohol spectrum disorders. Alcohol Clin Exp Res. 2001;25:283–7.
Bayley N. Bayley scales of infant development manual (BSID-II). San Antonio: The Psychological Corporation; 1993.
Hoyme HE, May PA, Kalberg WO, Kodituwakku P, Gossage JP, Trujillo PM, Buckley DG, Miller JH, Aragon AS, Khaole N, et al. A practical clinical approach to diagnosis of fetal alcohol spectrum disorders: clarification of the 1996 institute of medicine criteria. Pediatrics. 2005;115:39–47.
Takane Y. Shibayama: principal component analysis with external information on both subjects and variables. Psychometrika. 1991;56:97–120.
Takane Y, Hunter MA. Constrained principal component analysis: a comprehensive theory. AAECC. 2001;12:391–419.
Cattell RB, Vogelmann S. A comprehensive trial of the scree and kg criteria for determining the number of factors. Multivariate Behav Res. 1977;12:289–325.
Danesh J. Smoldering arteries? Low-grade inflammation and coronary heart disease. JAMA. 1999;282:2169–71.
Franceschi C, Bonafe M, Valensin S, Olivieri F, De Luca M, Ottaviani E, De Benedictis G. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann N Y Acad Sci. 2000;908:244–54.
Franceschi C, Campisi J. Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. J Gerontol A Biol Sci Med Sci. 2014;69(Suppl 1):S4–9.
Rohleder N. Stimulation of systemic low-grade inflammation by psychosocial stress. Psychosom Med. 2014;76:181–9.
Abdallah MW, Larsen N, Grove J, Norgaard-Pedersen B, Thorsen P, Mortensen EL, Hougaard DM. Amniotic fluid inflammatory cytokines: potential markers of immunologic dysfunction in autism spectrum disorders. World J Biol Psychiatry. 2013;14:528–38.
Singh VK, Warren RP, Odell JD, Cole P. Changes of soluble interleukin-2, interleukin-2 receptor, T8 antigen, and interleukin-1 in the serum of autistic children. Clin Immunol Immunopathol. 1991;61:448–55.
Napolioni V, Ober-Reynolds B, Szelinger S, Corneveaux JJ, Pawlowski T, Ober-Reynolds S, Kirwan J, Persico AM, Melmed RD, Craig DW, et al. Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder. J Neuroinflammation. 2013;10:38.
Pecorelli A, Cervellati F, Belmonte G, Montagner G, Waldon P, Hayek J, Gambari R, Valacchi G. Cytokines profile and peripheral blood mononuclear cells morphology in Rett and autistic patients. Cytokine. 2016;77:180–8.
Bodnar TS, Hill LA, Weinberg J. Evidence for an immune signature of prenatal alcohol exposure in female rats. Brain Behav Immun. 2016;58:130–41.
Provost V, Larose MC, Langlois A, Rola-Pleszczynski M, Flamand N, Laviolette M. CCL26/eotaxin-3 is more effective to induce the migration of eosinophils of asthmatics than CCL11/eotaxin-1 and CCL24/eotaxin-2. J Leukoc Biol. 2013;94:213–22.
Conroy DM, Williams TJ. Eotaxin and the attraction of eosinophils to the asthmatic lung. Respir Res. 2001;2:150–6.
Wu D, Zhou J, Bi H, Li L, Gao W, Huang M, Adcock IM, Barnes PJ, Yao X. CCL11 as a potential diagnostic marker for asthma? J Asthma. 2014;51:847–54.
Coleman JM, Naik C, Holguin F, Ray A, Ray P, Trudeau JB, Wenzel SE. Epithelial eotaxin-2 and eotaxin-3 expression: relation to asthma severity, luminal eosinophilia and age at onset. Thorax. 2012;67:1061–6.
Hoshino M, Takahashi M, Aoike N. Expression of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin immunoreactivity in asthmatic airways and its relationship to angiogenesis. J Allergy Clin Immunol. 2001;107:295–301.
Oleson DR, Magee RM, Donahoe RM, Falek A, Coles CD. Immunity and prenatal alcohol exposure. A pilot study in human adolescents. Adv Exp Med Biol. 1998;437:255–64.
Gauthier TW, Ping XD, Harris FL, Wong M, Elbahesh H, Brown LA. Fetal alcohol exposure impairs alveolar macrophage function via decreased glutathione availability. Pediatr Res. 2005;57:76–81.
Gauthier TW, Ping XD, Gabelaia L, Brown LA. Delayed neonatal lung macrophage differentiation in a mouse model of in utero ethanol exposure. Am J Physiol Lung Cell Mol Physiol. 2010;299:L8–16.
Gauthier TW, Young PA, Gabelaia L, Tang SM, Ping XD, Harris FL, Brown LA. In utero ethanol exposure impairs defenses against experimental group B streptococcus in the term Guinea pig lung. Alcohol Clin Exp Res. 2009;33:300–6.
Carson CG, Halkjaer LB, Jensen SM, Bisgaard H. Alcohol intake in pregnancy increases the child’s risk of atopic dermatitis. the COPSAC prospective birth cohort study of a high risk population. PLoS One. 2012;7:e42710.
Bertrand J, Floyd LL, Weber MK. Fetal Alcohol Syndrome Prevention Team DoBD, Developmental Disabilities NCoBD, Developmental Disabilities CfDC, Prevention: Guidelines for identifying and referring persons with fetal alcohol syndrome. MMWR Recomm Rep. 2005;54:1–14.
Khurana R, Moons L, Shafi S, Luttun A, Collen D, Martin JF, Carmeliet P, Zachary IC. Placental growth factor promotes atherosclerotic intimal thickening and macrophage accumulation. Circulation. 2005;111:2828–36.
Siervo M, Ruggiero D, Sorice R, Nutile T, Aversano M, Stephan BC, Ciullo M. Angiogenesis and biomarkers of cardiovascular risk in adults with metabolic syndrome. J Intern Med. 2010;268:338–47.
Cassidy A, Chiuve SE, Manson JE, Rexrode KM, Girman CJ, Rimm EB. Potential role for plasma placental growth factor in predicting coronary heart disease risk in women. Arterioscler Thromb Vasc Biol. 2009;29:134–9.
Danesh J, Whincup P, Walker M, Lennon L, Thomson A, Appleby P, Gallimore JR, Pepys MB. Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. BMJ. 2000;321:199–204.
Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest. 2003;111:1805–12.
Parkington HC, Coleman HA, Wintour EM, Tare M. Prenatal alcohol exposure: implications for cardiovascular function in the fetus and beyond. Clin Exp Pharmacol Physiol. 2010;37:e91–8.
Cook JC, Lynch ME, Coles CD. Association analysis: fetal alcohol Spectrum disorder and hypertension status in children and adolescents. Alcohol Clin Exp Res. 2019;43:1727–33.
Burd L, Deal E, Rios R, Adickes E, Wynne J, Klug MG. Congenital heart defects and fetal alcohol spectrum disorders. Congenit Heart Dis. 2007;2:250–5.
Turcotte LA, Aberle NS, Norby FL, Wang GJ, Ren J. Influence of prenatal ethanol exposure on vascular contractile response in rat thoracic aorta. Alcohol. 2002;26:75–81.
Nguyen VB, Probyn ME, Campbell F, Yin KV, Samuel CS, Zimanyi MA, Bertram JF, Black MJ, Moritz KM. Low-dose maternal alcohol consumption: effects in the hearts of offspring in early life and adulthood. Physiol Rep. 2014;2:1–12.
Copeland WE, Wolke D, Lereya ST, Shanahan L, Worthman C, Costello EJ. Childhood bullying involvement predicts low-grade systemic inflammation into adulthood. Proc Natl Acad Sci U S A. 2014;111:7570–5.
Coelho R, Viola TW, Walss-Bass C, Brietzke E, Grassi-Oliveira R. Childhood maltreatment and inflammatory markers: a systematic review. Acta Psychiatr Scand. 2014;129:180–92.
Wium-Andersen MK, Orsted DD, Nielsen SF, Nordestgaard BG. Elevated C-reactive protein levels, psychological distress, and depression in 73, 131 individuals. JAMA Psychiatry. 2013;70:176–84.
Danese A, Moffitt TE, Pariante CM, Ambler A, Poulton R, Caspi A. Elevated inflammation levels in depressed adults with a history of childhood maltreatment. Arch Gen Psychiatry. 2008;65:409–15.
Streissguth AP, Bookstein FL, Barr HM, Sampson PD, O'Malley K, Young JK. Risk factors for adverse life outcomes in fetal alcohol syndrome and fetal alcohol effects. J Dev Behav Pediatr. 2004;25:228–38.
Pei J, Denys K, Hughes J, Rasmussen C. Mental health issues in fetal alcohol spectrum disorder. J Ment Health. 2011;20:438–48.
Raineki C, Bodnar TS, Holman PJ, Baglot SL, Lan N, Weinberg J. Effects of early-life adversity on immune function are mediated by prenatal environment: role of prenatal alcohol exposure. Brain Behav Immun. 2017;66:210–20.
Del Boca FK, Darkes J. The validity of self-reports of alcohol consumption: state of the science and challenges for research. Addiction. 2003;98(Suppl 2):1–12.
Armstrong KH, Agazzi HC. The Bayley-III Cognitive Scale. In Bayley-III Clinical Use and Interpretation. In: Weiss LG, Oakland T, Ayland GP, editors. . Springfield: Elsevier; 2010. p. 29–45.
Harris SR, Megens AM, Backman CL, Hayes VE. Stability of the Bayley II Scales of Infant Development in a sample of low-risk and high-risk infants. Dev Med Child Neurol. 2005;47:820–3.
Hack M, Taylor HG, Drotar D, Schluchter M, Cartar L, Wilson-Costello D, Klein N, Friedman H, Mercuri-Minich N, Morrow M. Poor predictive validity of the Bayley Scales of Infant Development for cognitive function of extremely low birth weight children at school age. Pediatrics. 2005;116:333–41.
Niccols A, Latchman A. Stability of the Bayley mental scale of infant development with high-risk infants. Br J Dev Disabil. 2002;48:3–13.