Rotshenker S. Wallerian degeneration: the innate-immune response to traumatic nerve injury. J Neuroinflammation. 2011;8:109.
Article
CAS
PubMed
PubMed Central
Google Scholar
Liefner M, Siebert H, Sachse T, Michel U, Kollias G, Bruck W. The role of TNF-alpha during Wallerian degeneration. J Neuroimmunol. 2000;108:147–52.
Article
CAS
PubMed
Google Scholar
Chen G, Luo X, Wang W, Wang Y, Zhu F, Wang W. Interleukin-1beta promotes Schwann cells de-differentiation in Wallerian degeneration via the c-JUN/AP-1 pathway. Front Cell Neurosci. 2019;13:304.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hirata K, Kawabuchi M. Myelin phagocytosis by macrophages and nonmacrophages during Wallerian degeneration. Microsc Res Tech. 2002;57:541–7.
Article
PubMed
Google Scholar
Stoll G, Griffin JW, Li CY, Trapp BD. Wallerian degeneration in the peripheral nervous system: participation of both Schwann cells and macrophages in myelin degradation. J Neurocytol. 1989;18:671–83.
Article
CAS
PubMed
Google Scholar
Shamash S, Reichert F, Rotshenker S. The cytokine network of Wallerian degeneration: tumor necrosis factor-alpha, interleukin-1alpha, and interleukin-1beta. J Neurosci. 2002;22:3052–60.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kato K, Liu H, Kikuchi S, Myers RR, Shubayev VI. Immediate anti-tumor necrosis factor-alpha (etanercept) therapy enhances axonal regeneration after sciatic nerve crush. J Neurosci Res. 2010;88:360–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chen SH, Wu CC, Lin SC, Tseng WL, Huang TC, Yadav A, Lu FI, Liu YH, Lin SP, Hsueh YY. Investigation of Neuropathology after Nerve Release in Chronic Constriction Injury of Rat Sciatic Nerve. Int J Mol Sci. 2021;22:4746.
Article
CAS
PubMed
PubMed Central
Google Scholar
Li J, Wei GH, Huang H, Lan YP, Liu B, Liu H, Zhang W, Zuo YX. Nerve injury-related autoimmunity activation leads to chronic inflammation and chronic neuropathic pain. Anesthesiology. 2013;118:416–29.
Article
CAS
PubMed
Google Scholar
Kato N, Nemoto K, Kawaguchi M, Amako M, Arino H, Fujikawa K. Influence of chronic inflammation in peripheral target tissue on recovery of crushed nerve injury. J Orthop Sci. 2001;6:419–23.
Article
CAS
PubMed
Google Scholar
Buttner R, Schulz A, Reuter M, Akula AK, Mindos T, Carlstedt A, Riecken LB, Baader SL, Bauer R, Morrison H. Inflammaging impairs peripheral nerve maintenance and regeneration. Aging Cell. 2018;17: e12833.
Article
PubMed
PubMed Central
CAS
Google Scholar
Chen SH, Huang TC, Wang JY, Wu CC, Hsueh YY. Controllable forces for reproducible chronic constriction injury mimicking compressive neuropathy in rat sciatic nerve. J Neurosci Methods. 2020;335: 108615.
Article
PubMed
Google Scholar
Hsieh J, Nakashima K, Kuwabara T, Mejia E, Gage FH. Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc Natl Acad Sci U S A. 2004;101:16659–64.
Article
CAS
PubMed
PubMed Central
Google Scholar
Yao YL, Yang WM. Beyond histone and deacetylase: an overview of cytoplasmic histone deacetylases and their nonhistone substrates. J Biomed Biotechnol. 2011;2011: 146493.
Article
PubMed
CAS
Google Scholar
Greer CB, Tanaka Y, Kim YJ, Xie P, Zhang MQ, Park IH, Kim TH. Histone deacetylases positively regulate transcription through the elongation machinery. Cell Rep. 2015;13:1444–55.
Article
CAS
PubMed
PubMed Central
Google Scholar
Glozak MA, Sengupta N, Zhang X, Seto E. Acetylation and deacetylation of non-histone proteins. Gene. 2005;363:15–23.
Article
CAS
PubMed
Google Scholar
Wang TY, Chang MM, Li YJ, Huang TC, Chien S, Wu CC. Maintenance of HDACs and H3K9me3 prevents arterial flow-induced venous endothelial damage. Front Cell Dev Biol. 2021;9: 642150.
Article
PubMed
PubMed Central
Google Scholar
Wu LM, Wang J, Conidi A, Zhao C, Wang H, Ford Z, Zhang L, Zweier C, Ayee BG, Maurel P, et al. Zeb2 recruits HDAC-NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination. Nat Neurosci. 2016;19:1060–72.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rosenberg LH, Cattin AL, Fontana X, Harford-Wright E, Burden JJ, White IJ, Smith JG, Napoli I, Quereda V, Policarpi C, et al. HDAC3 regulates the transition to the homeostatic myelinating Schwann cell state. Cell Rep. 2018;25:2755-2765 e2755.
Article
CAS
PubMed
PubMed Central
Google Scholar
Brugger V, Duman M, Bochud M, Munger E, Heller M, Ruff S, Jacob C. Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration. Nat Commun. 2017;8:14272.
Article
CAS
PubMed
PubMed Central
Google Scholar
He X, Zhang L, Queme LF, Liu X, Lu A, Waclaw RR, Dong X, Zhou W, Kidd G, Yoon SO, et al. A histone deacetylase 3-dependent pathway delimits peripheral myelin growth and functional regeneration. Nat Med. 2018;24:338–51.
Article
CAS
PubMed
PubMed Central
Google Scholar
Cousens LS, Gallwitz D, Alberts BM. Different accessibilities in chromatin to histone acetylase. J Biol Chem. 1979;254:1716–23.
Article
CAS
PubMed
Google Scholar
Kukkar A, Singh N, Jaggi AS. Attenuation of neuropathic pain by sodium butyrate in an experimental model of chronic constriction injury in rats. J Formos Med Assoc. 2014;113:921–8.
Article
CAS
PubMed
Google Scholar
Chuang DM, Leng Y, Marinova Z, Kim HJ, Chiu CT. Multiple roles of HDAC inhibition in neurodegenerative conditions. Trends Neurosci. 2009;32:591–601.
Article
CAS
PubMed
Google Scholar
Genin M, Clement F, Fattaccioli A, Raes M, Michiels C. M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide. BMC Cancer. 2015;15:577.
Article
PubMed
PubMed Central
CAS
Google Scholar
Huang TC, Wu HL, Chen SH, Wang YT, Wu CC. Thrombomodulin facilitates peripheral nerve regeneration through regulating M1/M2 switching. J Neuroinflammation. 2020;17:240.
Article
PubMed
PubMed Central
CAS
Google Scholar
Huang CW, Lu SY, Huang TC, Huang BM, Sun HS, Yang SH, Chuang JI, Hsueh YY, Wu YT, Wu CC. FGF9 induces functional differentiation to Schwann cells from human adipose derived stem cells. Theranostics. 2020;10:2817–31.
Article
CAS
PubMed
PubMed Central
Google Scholar
Liou JY, Wu CC, Chen BR, Yen LB, Wu KK. Nonsteroidal anti-inflammatory drugs induced endothelial apoptosis by perturbing peroxisome proliferator-activated receptor-delta transcriptional pathway. Mol Pharmacol. 2008;74:1399–406.
Article
CAS
PubMed
Google Scholar
Fang SY, Huang CW, Huang TC, Yadav A, Chiu JJ, Wu CC. Reduction in microRNA-4488 expression induces NFkappaB translocation in venous endothelial cells under arterial flow. Cardiovasc Drugs Ther. 2021;35:61–71.
Article
CAS
PubMed
Google Scholar
Wu CC, Li YS, Haga JH, Kaunas R, Chiu JJ, Su FC, Usami S, Chien S. Directional shear flow and Rho activation prevent the endothelial cell apoptosis induced by micropatterned anisotropic geometry. Proc Natl Acad Sci U S A. 2007;104:1254–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hood B, Levene HB, Levi AD. Transplantation of autologous Schwann cells for the repair of segmental peripheral nerve defects. Neurosurg Focus. 2009;26:E4.
Article
PubMed
Google Scholar
Francel PC, Francel TJ, Mackinnon SE, Hertl C. Enhancing nerve regeneration across a silicone tube conduit by using interposed short-segment nerve grafts. J Neurosurg. 1997;87:887–92.
Article
CAS
PubMed
Google Scholar
Hsueh YY, Chang YJ, Huang TC, Fan SC, Wang DH, Chen JJ, Wu CC, Lin SC. Functional recoveries of sciatic nerve regeneration by combining chitosan-coated conduit and neurosphere cells induced from adipose-derived stem cells. Biomaterials. 2014;35:2234–44.
Article
CAS
PubMed
Google Scholar
Huang CW, Huang CC, Chen YL, Fan SC, Hsueh YY, Ho CJ, Wu CC. Shear stress induces differentiation of endothelial lineage cells to protect neonatal brain from hypoxic-ischemic injury through NRP1 and VEGFR2 signaling. Biomed Res Int. 2015;2015: 862485.
PubMed
PubMed Central
Google Scholar
Liu C, Tsai AL, Li PC, Huang CW, Wu CC. Endothelial differentiation of bone marrow mesenchyme stem cells applicable to hypoxia and increased migration through Akt and NFkappaB signals. Stem Cell Res Ther. 2017;8:29.
Article
PubMed
PubMed Central
CAS
Google Scholar
Crowe AR, Yue W. Semi-quantitative determination of protein expression using immunohistochemistry staining and analysis: an integrated protocol. Bio Protoc. 2019. https://doi.org/10.21769/BioProtoc.3465.
Article
PubMed
PubMed Central
Google Scholar
Thakur KK, Saini J, Mahajan K, Singh D, Jayswal DP, Mishra S, Bishayee A, Sethi G, Kunnumakkara AB. Therapeutic implications of toll-like receptors in peripheral neuropathic pain. Pharmacol Res. 2017;115:224–32.
Article
CAS
PubMed
Google Scholar
Iwamoto M, Nakamura Y, Takemura M, Hisaoka-Nakashima K, Morioka N. TLR4-TAK1-p38 MAPK pathway and HDAC6 regulate the expression of sigma-1 receptors in rat primary cultured microglia. J Pharmacol Sci. 2020;144:23–9.
Article
CAS
PubMed
Google Scholar
Liu T, Zhang L, Joo D, Sun SC. NF-kappaB signaling in inflammation. Signal Transduct Target Ther. 2017;2:17023.
Article
PubMed
PubMed Central
Google Scholar
Sharif O, Bolshakov VN, Raines S, Newham P, Perkins ND. Transcriptional profiling of the LPS induced NF-kappaB response in macrophages. BMC Immunol. 2007;8:1.
Article
PubMed
PubMed Central
CAS
Google Scholar
Choi S, Choi HJ, Cheong Y, Lim YJ, Park HK. Internal-specific morphological analysis of sciatic nerve fibers in a radiofrequency-induced animal neuropathic pain model. PLoS ONE. 2013;8: e73913.
Article
CAS
PubMed
PubMed Central
Google Scholar
Campana WM, Li X, Shubayev VI, Angert M, Cai K, Myers RR. Erythropoietin reduces Schwann cell TNF-alpha, Wallerian degeneration and pain-related behaviors after peripheral nerve injury. Eur J Neurosci. 2006;23:617–26.
Article
PubMed
Google Scholar
Li X, Wang S, Yang X, Chu H. miR1423p targets AC9 to regulate sciatic nerve injuryinduced neuropathic pain by regulating the cAMP/AMPK signalling pathway. Int J Mol Med. 2021;47:561–72.
Article
CAS
PubMed
Google Scholar
Kato N, Matsumoto M, Kogawa M, Atkins GJ, Findlay DM, Fujikawa T, Oda H, Ogata M. Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo. J Neuroinflammation. 2013;10:1.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kiefer R, Kieseier BC, Stoll G, Hartung HP. The role of macrophages in immune-mediated damage to the peripheral nervous system. Prog Neurobiol. 2001;64:109–27.
Article
CAS
PubMed
Google Scholar
Bollaerts I, Van Houcke J, Andries L, De Groef L, Moons L. Neuroinflammation as fuel for axonal regeneration in the injured vertebrate central nervous system. Mediators Inflamm. 2017;2017:9478542.
Article
PubMed
PubMed Central
CAS
Google Scholar
Yong VW, Rivest S. Taking advantage of the systemic immune system to cure brain diseases. Neuron. 2009;64:55–60.
Article
CAS
PubMed
Google Scholar
Sawada T, Sano M, Omura T, Omura K, Hasegawa T, Funahashi S, Nagano A. Spatiotemporal quantification of tumor necrosis factor-alpha and interleukin-10 after crush injury in rat sciatic nerve utilizing immunohistochemistry. Neurosci Lett. 2007;417:55–60.
Article
CAS
PubMed
Google Scholar
Omura T, Omura K, Sano M, Sawada T, Hasegawa T, Nagano A. Spatiotemporal quantification of recruit and resident macrophages after crush nerve injury utilizing immunohistochemistry. Brain Res. 2005;1057:29–36.
Article
CAS
PubMed
Google Scholar
Taskinen HS, Roytta M. The dynamics of macrophage recruitment after nerve transection. Acta Neuropathol. 1997;93:252–9.
Article
CAS
PubMed
Google Scholar
Ydens E, Cauwels A, Asselbergh B, Goethals S, Peeraer L, Lornet G, Almeida-Souza L, Van Ginderachter JA, Timmerman V, Janssens S. Acute injury in the peripheral nervous system triggers an alternative macrophage response. J Neuroinflammation. 2012;9:176.
Article
CAS
PubMed
PubMed Central
Google Scholar
Myers RR, Sekiguchi Y, Kikuchi S, Scott B, Medicherla S, Protter A, Campana WM. Inhibition of p38 MAP kinase activity enhances axonal regeneration. Exp Neurol. 2003;184:606–14.
Article
CAS
PubMed
Google Scholar
McCully ML, Kouzeli A, Moser B. Peripheral tissue chemokines: homeostatic control of immune surveillance T cells. Trends Immunol. 2018;39:734–47.
Article
CAS
PubMed
Google Scholar
Kim HJ, Rowe M, Ren M, Hong JS, Chen PS, Chuang DM. Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. J Pharmacol Exp Ther. 2007;321:892–901.
Article
CAS
PubMed
Google Scholar
Tang YH, Yue ZS, Zheng WJ, Shen HF, Zeng LR, Hu ZQ, Xiong ZF. 4-Phenylbutyric acid presents therapeutic effect on osteoarthritis via inhibiting cell apoptosis and inflammatory response induced by endoplasmic reticulum stress. Biotechnol Appl Biochem. 2018;65:540–6.
Article
CAS
PubMed
Google Scholar
Zeng M, Sang W, Chen S, Chen R, Zhang H, Xue F, Li Z, Liu Y, Gong Y, Zhang H, Kong X. 4-PBA inhibits LPS-induced inflammation through regulating ER stress and autophagy in acute lung injury models. Toxicol Lett. 2017;271:26–37.
Article
CAS
PubMed
Google Scholar
Lim EF, Hoghooghi V, Hagen KM, Kapoor K, Frederick A, Finlay TM, Ousman SS. Presence and activation of pro-inflammatory macrophages are associated with CRYAB expression in vitro and after peripheral nerve injury. J Neuroinflammation. 2021;18:82.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gonzalez-Jaramillo V, Portilla-Fernandez E, Glisic M, Voortman T, Ghanbari M, Bramer W, Chowdhury R, Nijsten T, Dehghan A, Franco OH, Nano J. Epigenetics and inflammatory markers: a systematic review of the current evidence. Int J Inflam. 2019;2019:6273680.
PubMed
PubMed Central
Google Scholar
Leoni F, Fossati G, Lewis EC, Lee JK, Porro G, Pagani P, Modena D, Moras ML, Pozzi P, Reznikov LL, et al. The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo. Mol Med. 2005;11:1–15.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kawabata T, Nishida K, Takasugi K, Ogawa H, Sada K, Kadota Y, Inagaki J, Hirohata S, Ninomiya Y, Makino H. Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis. Arthritis Res Ther. 2010;12:R133.
Article
PubMed
PubMed Central
CAS
Google Scholar
Chung YL, Lee MY, Wang AJ, Yao LF. A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis. Mol Ther. 2003;8:707–17.
Article
CAS
PubMed
Google Scholar
Blanchard F, Chipoy C. Histone deacetylase inhibitors: new drugs for the treatment of inflammatory diseases? Drug Discov Today. 2005;10:197–204.
Article
CAS
PubMed
Google Scholar
Wu F, Xing D, Peng Z, Rao T. Enhanced rat sciatic nerve regeneration through silicon tubes implanted with valproic acid. J Reconstr Microsurg. 2008;24:267–76.
Article
PubMed
Google Scholar
Rao T, Wu F, Xing D, Peng Z, Ren D, Feng W, Chen Y, Zhao Z, Wang H, Wang J, et al. Effects of valproic acid on axonal regeneration and recovery of motor function after peripheral nerve injury in the rat. Arch Bone Jt Surg. 2014;2:17–24.
PubMed
PubMed Central
Google Scholar
Pan HC, Cheng FC, Chen CJ, Lai SZ, Liu MJ, Chang MH, Wang YC, Yang DY, Ho SP. Dietary supplement with fermented soybeans, natto, improved the neurobehavioral deficits after sciatic nerve injury in rats. Neurol Res. 2009;31:441–52.
Article
CAS
PubMed
Google Scholar
Wu SC, Rau CS, Lu TH, Wu CJ, Wu YC, Tzeng SL, Chen YC, Hsieh CH. Knockout of TLR4 and TLR2 impair the nerve regeneration by delayed demyelination but not remyelination. J Biomed Sci. 2013;20:62.
Article
CAS
PubMed
PubMed Central
Google Scholar
Boivin A, Pineau I, Barrette B, Filali M, Vallieres N, Rivest S, Lacroix S. Toll-like receptor signaling is critical for Wallerian degeneration and functional recovery after peripheral nerve injury. J Neurosci. 2007;27:12565–76.
Article
CAS
PubMed
Google Scholar
Sauer RS, Hackel D, Morschel L, Sahlbach H, Wang Y, Mousa SA, Roewer N, Brack A, Rittner HL. Toll like receptor (TLR)-4 as a regulator of peripheral endogenous opioid-mediated analgesia in inflammation. Mol Pain. 2014;10:10.
Article
PubMed
PubMed Central
CAS
Google Scholar
Chen X, Barozzi I, Termanini A, Prosperini E, Recchiuti A, Dalli J, Mietton F, Matteoli G, Hiebert S, Natoli G. Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages. Proc Natl Acad Sci U S A. 2012;109:E2865-2874.
Article
CAS
PubMed
PubMed Central
Google Scholar
Leus NG, van der Wouden PE, van den Bosch T, Hooghiemstra WTR, Ourailidou ME, Kistemaker LE, Bischoff R, Gosens R, Haisma HJ, Dekker FJ. HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-kappaB p65 transcriptional activity. Biochem Pharmacol. 2016;108:58–74.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ma J, Luo T, Zeng Z, Fu H, Asano Y, Liao Y, Minamino T, Kitakaze M. Histone deacetylase inhibitor phenylbutyrate exaggerates heart failure in pressure overloaded mice independently of HDAC inhibition. Sci Rep. 2016;6:34036.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ji MH, Li GM, Jia M, Zhu SH, Gao DP, Fan YX, Wu J, Yang JJ. Valproic acid attenuates lipopolysaccharide-induced acute lung injury in mice. Inflammation. 2013;36:1453–9.
Article
CAS
PubMed
Google Scholar